PMID- 19375385
OWN - NLM
STAT- MEDLINE
DCOM- 20090630
LR  - 20090512
IS  - 1872-8952 (Electronic)
IS  - 1388-2457 (Linking)
VI  - 120
IP  - 5
DP  - 2009 May
TI  - Inter-rater reliability of motor unit number estimates and quantitative motor 
      unit analysis in the tibialis anterior muscle.
PG  - 947-52
LID - 10.1016/j.clinph.2009.02.168 [doi]
AB  - OBJECTIVE: To establish the inter-rater reliability of decomposition-based 
      quantitative electromyography (DQEMG) derived motor unit number estimates (MUNEs) 
      and quantitative motor unit (MU) analysis. METHODS: Using DQEMG, two examiners 
      independently obtained a sample of needle and surface-detected motor unit 
      potentials (MUPs) from the tibialis anterior muscle from 10 subjects. Coupled 
      with a maximal M wave, surface-detected MUPs were used to derive a MUNE for each 
      subject and each examiner. Additionally, size-related parameters of the 
      individual MUs were obtained following quantitative MUP analysis. RESULTS: 
      Test-retest MUNE values were similar with high reliability observed between 
      examiners (ICC=0.87). Additionally, MUNE variability from test-retest as 
      quantified by a 95% confidence interval was relatively low (+/-28 MUs). Lastly, 
      quantitative data pertaining to MU size, complexity and firing rate were similar 
      between examiners. CONCLUSION: MUNEs and quantitative MU data can be obtained 
      with high reliability by two independent examiners using DQEMG. SIGNIFICANCE: 
      Establishing the inter-rater reliability of MUNEs and quantitative MU analysis 
      using DQEMG is central to the clinical applicability of the technique. In 
      addition to assessing response to treatments over time, multiple clinicians may 
      be involved in the longitudinal assessment of the MU pool of individuals with 
      disorders of the central or peripheral nervous system.
FAU - Boe, S G
AU  - Boe SG
AD  - Canadian Centre for Activity and Aging, School of Kinesiology, The University of 
      Western Ontario, Ont., Canada. boe.shaun@torontorehab.on.ca
FAU - Dalton, B H
AU  - Dalton BH
FAU - Harwood, B
AU  - Harwood B
FAU - Doherty, T J
AU  - Doherty TJ
FAU - Rice, C L
AU  - Rice CL
LA  - eng
PT  - Journal Article
DEP - 20090416
PL  - Netherlands
TA  - Clin Neurophysiol
JT  - Clinical neurophysiology : official journal of the International Federation of 
      Clinical Neurophysiology
JID - 100883319
SB  - IM
MH  - Action Potentials/physiology
MH  - Adult
MH  - Cell Count/methods
MH  - Electrodes
MH  - Humans
MH  - Leg/anatomy & histology/*physiology
MH  - Male
MH  - Motor Neurons/*physiology
MH  - Muscle, Skeletal/*innervation/*physiology
MH  - Neuromuscular Junction/*physiology
MH  - Observer Variation
MH  - Predictive Value of Tests
MH  - Reproducibility of Results
MH  - Signal Processing, Computer-Assisted
MH  - Young Adult
EDAT- 2009/04/21 09:00
MHDA- 2009/07/01 09:00
CRDT- 2009/04/21 09:00
PHST- 2008/10/09 00:00 [received]
PHST- 2009/01/28 00:00 [revised]
PHST- 2009/02/24 00:00 [accepted]
PHST- 2009/04/21 09:00 [entrez]
PHST- 2009/04/21 09:00 [pubmed]
PHST- 2009/07/01 09:00 [medline]
AID - S1388-2457(09)00232-6 [pii]
AID - 10.1016/j.clinph.2009.02.168 [doi]
PST - ppublish
SO  - Clin Neurophysiol. 2009 May;120(5):947-52. doi: 10.1016/j.clinph.2009.02.168. 
      Epub 2009 Apr 16.