PMID- 19378696 OWN - NLM STAT- MEDLINE DCOM- 20090603 LR - 20220409 IS - 1121-189X (Print) IS - 1121-189X (Linking) VI - 18 IP - 1 DP - 2009 Jan-Mar TI - The global burden of mental disorders: an update from the WHO World Mental Health (WMH) surveys. PG - 23-33 AB - AIMS: The paper reviews recent findings from the WHO World Mental Health (WMH) surveys on the global burden of mental disorders. METHODS: The WMH surveys are representative community surveys in 28 countries throughout the world aimed at providing information to mental health policy makers about the prevalence, distribution, burden, and unmet need for treatment of common mental disorders. RESULTS: The first 17 WMH surveys show that mental disorders are commonly occurring in all participating countries. The inter-quartile range (IQR: 25th-75th percentiles) of lifetime DSM-IV disorder prevalence estimates (combining anxiety, mood, externalizing, and substance use disorders) is 18.1-36.1%. The IQR of 12-month prevalence estimates is 9.8-19.1%. Prevalence estimates of 12-month Serious Mental Illness (SMI) are 4-6.8% in half the countries, 2.3-3.6% in one-fourth, and 0.8-1.9% in one-fourth. Many mental disorders begin in childhood-adolescence and have significant adverse effects on subsequent role transitions in the WMH data. Adult mental disorders are found to be associated with such high role impairment in the WMH data that available clinical interventions could have positive cost-effectiveness ratios. CONCLUSIONS: Mental disorders are commonly occurring and often seriously impairing in many countries throughout the world. Expansion of treatment could be cost-effective from both employer and societal perspectives. FAU - Kessler, Ronald C AU - Kessler RC AD - Department of Health Care Policy, Harvard Medical School, 180 Longwood Avenue, Boston, MA 02115, USA. Kessler@hcp.med.harvard.edu FAU - Aguilar-Gaxiola, Sergio AU - Aguilar-Gaxiola S FAU - Alonso, Jordi AU - Alonso J FAU - Chatterji, Somnath AU - Chatterji S FAU - Lee, Sing AU - Lee S FAU - Ormel, Johan AU - Ormel J FAU - Ustun, T Bedirhan AU - Ustun TB FAU - Wang, Philip S AU - Wang PS LA - eng GR - R01 DA016558/DA/NIDA NIH HHS/United States GR - R01 MH070884-05/MH/NIMH NIH HHS/United States GR - U01 MH060220-10/MH/NIMH NIH HHS/United States GR - R01 DA016558-06/DA/NIDA NIH HHS/United States GR - K05 DA015799/DA/NIDA NIH HHS/United States GR - U01 MH060220/MH/NIMH NIH HHS/United States GR - R01 MH070884/MH/NIMH NIH HHS/United States GR - U01MH060220/MH/NIMH NIH HHS/United States GR - R01 DA012058-05/DA/NIDA NIH HHS/United States GR - R01 DA012058/DA/NIDA NIH HHS/United States PT - Journal Article PT - Research Support, N.I.H., Extramural PL - Italy TA - Epidemiol Psichiatr Soc JT - Epidemiologia e psichiatria sociale JID - 9501447 SB - IM MH - Cost of Illness MH - Data Collection MH - *Global Health MH - Humans MH - Mental Disorders/complications/*epidemiology MH - Prevalence MH - Severity of Illness Index MH - Time Factors MH - World Health Organization PMC - PMC3039289 MID - NIHMS264248 COIS- Declaration of Interest: Professor Kessler has been a consultant for GlaxoSmithKline Inc., Pfizer Inc., Wyeth-Ayerst, Sanofi-Aventis, Kaiser Permanente, and Shire Pharmaceuticals; has served on advisory boards for Eli Lilly & Company and Wyeth-Ayerst; and has had research support for his epidemiological studies from Eli Lilly and Company, Pfizer Inc., Ortho-McNeil Pharmaceuticals Inc., and Bristol-Myers Squibb. EDAT- 2009/04/22 09:00 MHDA- 2009/06/06 09:00 PMCR- 2011/02/15 CRDT- 2009/04/22 09:00 PHST- 2009/04/22 09:00 [entrez] PHST- 2009/04/22 09:00 [pubmed] PHST- 2009/06/06 09:00 [medline] PHST- 2011/02/15 00:00 [pmc-release] AID - 10.1017/s1121189x00001421 [doi] PST - ppublish SO - Epidemiol Psichiatr Soc. 2009 Jan-Mar;18(1):23-33. doi: 10.1017/s1121189x00001421.