PMID- 19379611
OWN - NLM
STAT- MEDLINE
DCOM- 20090526
LR  - 20220311
IS  - 1945-8924 (Print)
IS  - 1945-8932 (Linking)
VI  - 23
IP  - 1
DP  - 2009 Jan-Feb
TI  - Validation of the Sino-Nasal Outcome Test 20 (SNOT-20) domains in nonsurgical 
      patients.
PG  - 40-5
LID - 10.2500/ajra.2009.23.3259 [doi]
AB  - BACKGROUND: The objectives of this study were, first, to confirm the presence of 
      multiple domains within the Sino-Nasal Outcome Test 20 (SNOT-20) using a 
      medically treated population, and, second, to reanalyze data from this population 
      to reveal incremental information. A prospective, randomized controlled trial was 
      performed. METHODS: One hundred twenty-seven adults with chronic rhinitis or 
      rhinosinusitis symptoms were treated with nasal saline irrigation or spray. 
      Treatment outcome was quality of life measured with SNOT-20 scores, which were 
      reanalyzed for this study with a factor analysis. Differences in change scores 
      were compared. RESULTS: Factor analysis confirmed the presence of four domains: 
      psychological function, sleep function, rhinological symptoms, and ear and/or 
      facial symptoms. At 8 weeks after randomization, saline irrigation had 
      significant effects on the rhinological symptom (p = 0.01) and sleep (p = 0.01) 
      compared with saline spray, but no between-group difference was seen in 
      psychological function or ear and/or facial symptom domains. CONCLUSION: 
      Subscales identified differences in the impact of two medical interventions on 
      chronic sinonasal symptoms. Reporting subscale scores might improve the precision 
      of the SNOT-20 instrument, allowing discrimination between various treatments and 
      their differential impact on sinonasal quality of life.
FAU - Pynnonen, Melissa A
AU  - Pynnonen MA
AD  - Department of Otolaryngology, University of Michigan Health System, Ann Arbor, 
      Michigan, USA. pynnonen@umich.edu
FAU - Kim, H Myra
AU  - Kim HM
FAU - Terrell, Jeffrey E
AU  - Terrell JE
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Randomized Controlled Trial
PL  - United States
TA  - Am J Rhinol Allergy
JT  - American journal of rhinology & allergy
JID - 101490775
RN  - 451W47IQ8X (Sodium Chloride)
SB  - IM
MH  - Administration, Intranasal
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Nasal Lavage/*methods
MH  - Prospective Studies
MH  - Quality of Life
MH  - Reproducibility of Results
MH  - Rhinitis/complications/diagnosis/*drug therapy
MH  - Severity of Illness Index
MH  - Sinusitis/complications/diagnosis/*drug therapy
MH  - Sodium Chloride/*administration & dosage
MH  - Treatment Outcome
EDAT- 2009/04/22 09:00
MHDA- 2009/05/27 09:00
CRDT- 2009/04/22 09:00
PHST- 2009/04/22 09:00 [entrez]
PHST- 2009/04/22 09:00 [pubmed]
PHST- 2009/05/27 09:00 [medline]
AID - 10.2500/ajra.2009.23.3259 [doi]
PST - ppublish
SO  - Am J Rhinol Allergy. 2009 Jan-Feb;23(1):40-5. doi: 10.2500/ajra.2009.23.3259.