PMID- 19379647 OWN - NLM STAT- MEDLINE DCOM- 20090624 LR - 20090421 IS - 1087-2108 (Electronic) IS - 1087-2108 (Linking) VI - 15 IP - 3 DP - 2009 Mar 15 TI - Atypical histopathology in bowel-associated dermatosis-arthritis syndrome: A case report. PG - 3 AB - Bowel-associated dermatosis-arthritis syndrome (BADAS) is characterized by a prodrome of fever, chills, and flu-like symptoms with subsequent skin eruptions, myalgias, and polyarthralgias. The syndrome was initially described following jejunoileal bypass surgery for weight loss. Histopathology of the skin lesions present in BADAS is described in the literature as identical to that of Sweet syndrome. We present a patient whose clinical history and physical exam were consistent with the diagnosis of BADAS. Dermatopathology in this case demonstrated a large subcorneal pustule without a significant dermal neutrophilic infiltrate. The histologic differential included subcorneal pustular dermatosis, bullous impetigo, or IgA pemphigus. The histology in BADAS may not necessarily be identical to Sweet syndrome, and the clinical picture alone plays an important role in diagnosis. The correct diagnosis of BADAS prevents a myriad of laboratory tests and allows for more effective symptom management in this chronic condition. FAU - Patton, Timothy AU - Patton T AD - Department of Dermatology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA. pattontj@upmc.edu FAU - Jukic, Drazen AU - Jukic D FAU - Juhas, Elizabeth AU - Juhas E LA - eng PT - Case Reports PT - Journal Article DEP - 20090315 PL - United States TA - Dermatol Online J JT - Dermatology online journal JID - 9610776 RN - 0 (Antigens, Bacterial) SB - IM MH - Antigens, Bacterial/immunology MH - Arthralgia/diagnosis/etiology/immunology/*pathology MH - Arthritis/diagnosis/etiology/immunology/*pathology MH - Chills/etiology MH - Diagnosis, Differential MH - Erythema/diagnosis/etiology/immunology/*pathology MH - Female MH - Fever/etiology MH - *Gastric Bypass MH - Humans MH - Impetigo/diagnosis MH - Intestines/microbiology MH - Middle Aged MH - Neutrophils/pathology MH - Pemphigus/diagnosis MH - Postoperative Complications/etiology/immunology/*pathology MH - Skin Diseases, Vesiculobullous/diagnosis MH - Sweet Syndrome/diagnosis EDAT- 2009/04/22 09:00 MHDA- 2009/06/25 09:00 CRDT- 2009/04/22 09:00 PHST- 2009/04/22 09:00 [entrez] PHST- 2009/04/22 09:00 [pubmed] PHST- 2009/06/25 09:00 [medline] PST - epublish SO - Dermatol Online J. 2009 Mar 15;15(3):3.