PMID- 19385373
OWN - NLM
STAT- MEDLINE
DCOM- 20090507
LR  - 20211020
IS  - 0017-8594 (Print)
IS  - 0017-8594 (Linking)
VI  - 68
IP  - 2
DP  - 2009 Mar
TI  - Hansen's disease with HIV: a case of immune reconstitution disease.
PG  - 27-9
AB  - Immune reconstitution inflammatory syndrome (IRIS) is an acute symptomatic 
      expression of a latent infection during the recovery of the immune system usually 
      as a response to antiretroviral therapy (ART). Opportunistic infections can 
      trigger IRIS. Hansen's disease is an infection caused by Mycobacterium leprae (M. 
      leprae). There have been a limited number of case reports reporting the 
      presentation of the co-infection of HIV and M. leprae. We report an unique case 
      of IRIS in a patient co-infected with HIV and M. leprae presenting as an 
      exacerbation of his Hansen's Disease where the patient's skin lesions progressed 
      from borderline tuberculoid to lepromatous leprosy following ART administration.
FAU - Chow, Dominic
AU  - Chow D
AD  - Department of Medicine, John A Burns School of Medicine, University of Hawai'i at 
      Manoa, Honolulu, HI 96813, USA. dominicc@hawaii.edu
FAU - Okinaka, Leila
AU  - Okinaka L
FAU - Souza, Scott
AU  - Souza S
FAU - Shikuma, Cecilia
AU  - Shikuma C
FAU - Tice, Alan
AU  - Tice A
LA  - eng
GR  - R25 RR019321/RR/NCRR NIH HHS/United States
GR  - R25 RR019321-01/RR/NCRR NIH HHS/United States
GR  - 1 R25 RR019321/RR/NCRR NIH HHS/United States
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PL  - United States
TA  - Hawaii Med J
JT  - Hawaii medical journal
JID - 2984209R
RN  - 0 (Anti-Retroviral Agents)
SB  - IM
MH  - Adult
MH  - Anti-Retroviral Agents/immunology
MH  - Comorbidity
MH  - HIV Infections/drug therapy/*epidemiology/immunology
MH  - Humans
MH  - Immune Reconstitution Inflammatory Syndrome/*epidemiology
MH  - Leprosy/*epidemiology/immunology
MH  - Male
PMC - PMC2714697
MID - NIHMS107566
EDAT- 2009/04/24 09:00
MHDA- 2009/05/08 09:00
PMCR- 2009/07/23
CRDT- 2009/04/24 09:00
PHST- 2009/04/24 09:00 [entrez]
PHST- 2009/04/24 09:00 [pubmed]
PHST- 2009/05/08 09:00 [medline]
PHST- 2009/07/23 00:00 [pmc-release]
PST - ppublish
SO  - Hawaii Med J. 2009 Mar;68(2):27-9.