PMID- 19392689
OWN - NLM
STAT- MEDLINE
DCOM- 20090921
LR  - 20220330
IS  - 1365-313X (Electronic)
IS  - 0960-7412 (Linking)
VI  - 59
IP  - 3
DP  - 2009 Aug
TI  - The Arabidopsis ABA-INSENSITIVE (ABI) 4 factor acts as a central transcription 
      activator of the expression of its own gene, and for the induction of ABI5 and 
      SBE2.2 genes during sugar signaling.
PG  - 359-74
LID - 10.1111/j.1365-313X.2009.03877.x [doi]
AB  - The transcription factor ABA INSENSITIVE 4 (ABI4), discovered nearly 10 years 
      ago, plays a central role in a variety of functions in plants, including sugar 
      responses. However, not until very recently has its mechanism of action begun to 
      be elucidated. Modulating gene expression is one of the primary mechanisms of 
      sugar regulation in plants. Nevertheless, the transcription factors involved in 
      regulating sugar responses and their role(s) during the signal transduction 
      cascade remain poorly defined. In this paper we analyzed the participation of 
      ABI4, as it is one of the main transcription factors implicated in glucose 
      signaling during early seedling development. Our studies show that ABI4 is an 
      essential activator of its own expression during development, in ABA signaling 
      and in sugar responses. It is also important for the glucose-mediated expression 
      of the genes ABI5 and SBE2.2. We demonstrate that ABI4 binds directly to the 
      promoter region of all three genes and activates their expression in vivo through 
      at CE1-like element. Previous studies found that ABI4 also functions as a 
      transcriptional repressor of sugar-regulated genes, therefore this transcription 
      factor is a versatile protein with dual functions for modulating gene expression.
FAU - Bossi, Flavia
AU  - Bossi F
AD  - Departamento de Biologia Molecular de Plantas, Instituto de Biotecnologia, 
      Universidad Nacional Autonoma de Mexico, Morelos, Mexico.
FAU - Cordoba, Elizabeth
AU  - Cordoba E
FAU - Dupre, Patricia
AU  - Dupre P
FAU - Mendoza, Monica Santos
AU  - Mendoza MS
FAU - Roman, Carolina San
AU  - Roman CS
FAU - Leon, Patricia
AU  - Leon P
LA  - eng
GR  - Howard Hughes Medical Institute/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20090326
PL  - England
TA  - Plant J
JT  - The Plant journal : for cell and molecular biology
JID - 9207397
RN  - 0 (ABI4 protein, Arabidopsis)
RN  - 0 (ABI5 protein, Arabidopsis)
RN  - 0 (Arabidopsis Proteins)
RN  - 0 (Basic-Leucine Zipper Transcription Factors)
RN  - 0 (RNA, Plant)
RN  - 0 (Transcription Factors)
RN  - 72S9A8J5GW (Abscisic Acid)
RN  - IY9XDZ35W2 (Glucose)
SB  - IM
MH  - Abscisic Acid/metabolism
MH  - Arabidopsis/genetics/*metabolism
MH  - Arabidopsis Proteins/genetics/*metabolism
MH  - Base Sequence
MH  - Basic-Leucine Zipper Transcription Factors/*metabolism
MH  - Gene Expression Regulation, Plant
MH  - Glucose/metabolism
MH  - Molecular Sequence Data
MH  - Promoter Regions, Genetic
MH  - Protein Binding
MH  - RNA, Plant/genetics
MH  - Seedlings/growth & development
MH  - Signal Transduction
MH  - Transcription Factors/genetics/*metabolism
MH  - Transcription Initiation Site
EDAT- 2009/04/28 09:00
MHDA- 2009/09/22 06:00
CRDT- 2009/04/28 09:00
PHST- 2009/04/28 09:00 [entrez]
PHST- 2009/04/28 09:00 [pubmed]
PHST- 2009/09/22 06:00 [medline]
AID - TPJ3877 [pii]
AID - 10.1111/j.1365-313X.2009.03877.x [doi]
PST - ppublish
SO  - Plant J. 2009 Aug;59(3):359-74. doi: 10.1111/j.1365-313X.2009.03877.x. Epub 2009 
      Mar 26.