PMID- 19409960
OWN - NLM
STAT- MEDLINE
DCOM- 20090821
LR  - 20090601
IS  - 1872-7972 (Electronic)
IS  - 0304-3940 (Linking)
VI  - 459
IP  - 1
DP  - 2009 Jul 31
TI  - Neural bases of behavior selection without an objective correct answer.
PG  - 30-4
LID - 10.1016/j.neulet.2009.04.056 [doi]
AB  - Life choice (e.g. occupation choice) often includes situations with two or more 
      possible answers. How does the brain respond to such conflict-ridden situations? 
      We investigated whether the dorsal anterior cingulate cortex (dACC) evaluates the 
      degree of conflict between possible answers. Additionally, we investigated 
      whether the medial prefrontal cortex (MPFC) or the medial temporal lobe (MTL) has 
      a function in behavior selection with plural possible answers. We used an 
      occupational choice task (e.g. which occupation do you think you could do 
      better?-dancer or chemist) with two possible answers and a word-length task (e.g. 
      which word is longer?-dentist or comedian) that has a correct answer. The 
      conflicts in each task were manipulated. Results showed that the dACC and the MTL 
      were activated when the conflict during occupational choice was large, and that 
      the MPFC and posterior cingulate cortex were activated more in the occupational 
      choice task than in the word-length task. Our results show that the dACC 
      evaluates the degree of conflict between possible answers, and that the MTL, 
      MPFC, and posterior cingulate cortex have a function in behavior selection 
      without an objective correct answer. It is thought that the MTL functions to 
      reduce conflict when a large-conflict is detected in the dACC. Furthermore, the 
      MPFC and posterior cingulate are thought to have a function of biasing any of the 
      plural answers in behavior selection without an objective answer.
FAU - Nakao, Takashi
AU  - Nakao T
AD  - Japan Society for the Promotion of Science (JSPS), Japan. 
      takana818@lit.nagoya-u.ac.jp
FAU - Osumi, Takahiro
AU  - Osumi T
FAU - Ohira, Hideki
AU  - Ohira H
FAU - Kasuya, Yukinori
AU  - Kasuya Y
FAU - Shinoda, Jun
AU  - Shinoda J
FAU - Yamada, Jitsuhiro
AU  - Yamada J
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20090504
PL  - Ireland
TA  - Neurosci Lett
JT  - Neuroscience letters
JID - 7600130
SB  - IM
MH  - Adult
MH  - Analysis of Variance
MH  - Brain/*physiology
MH  - Brain Mapping
MH  - Choice Behavior/*physiology
MH  - Female
MH  - Gyrus Cinguli/physiology
MH  - Humans
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Occupations
MH  - Prefrontal Cortex/physiology
MH  - Temporal Lobe/physiology
MH  - Young Adult
EDAT- 2009/05/05 09:00
MHDA- 2009/08/22 09:00
CRDT- 2009/05/05 09:00
PHST- 2009/03/10 00:00 [received]
PHST- 2009/04/20 00:00 [revised]
PHST- 2009/04/25 00:00 [accepted]
PHST- 2009/05/05 09:00 [entrez]
PHST- 2009/05/05 09:00 [pubmed]
PHST- 2009/08/22 09:00 [medline]
AID - S0304-3940(09)00578-3 [pii]
AID - 10.1016/j.neulet.2009.04.056 [doi]
PST - ppublish
SO  - Neurosci Lett. 2009 Jul 31;459(1):30-4. doi: 10.1016/j.neulet.2009.04.056. Epub 
      2009 May 4.