PMID- 19413739
OWN - NLM
STAT- MEDLINE
DCOM- 20110420
LR  - 20131121
IS  - 1537-2995 (Electronic)
IS  - 0041-1132 (Linking)
VI  - 49
IP  - 8
DP  - 2009 Aug
TI  - Simple standing test predicts and water ingestion prevents vasovagal reaction in 
      the high-risk blood donors.
PG  - 1630-6
LID - 10.1111/j.1537-2995.2009.02189.x [doi]
AB  - BACKGROUND: One of the serious complications of blood donation is vasovagal 
      reaction (VVR) with syncope. This study was performed to determine if the 
      measurement of hemodynamic responses to standing before blood collection (BC) was 
      useful to identify the high-risk donors for VVR and also examined the effect of 
      300 mL of water ingestion in the prevention of VVR. STUDY DESIGN AND METHODS: 
      Blood pressure and heart rate (HR) during 5 minutes of standing were examined 
      before and after BC in 93 donors. Because HR increase of 6 of 7 donors who 
      developed syncopal VVR during standing after BC was 15 beats per minute (bpm) or 
      greater, those with HR increase of 15 bpm or greater were determined as high-risk 
      donors (n = 31). In another group (n = 117), 45 donors were identified as high 
      risk based on the HR response before BC (15 bpm). The effect of 300 mL of water 
      ingestion 15 minutes before BC on hemodynamic responses to standing and the rate 
      of VVR after BC were analyzed. RESULTS: Water ingestion given to the high-risk 
      donors of the second group reduced HR increase with standing before BC (-6.6 +/- 
      13.6 bpm, p < 0.02 vs. HR increase before water ingestion) and significantly 
      suppressed VVR rate (2 of 45 donors with high risk, 4.4%,p < 0.04 vs. the first 
      group; 6 of 31 high-risk donors, 19.4%). CONCLUSION: HR response to standing 
      before BC may detect the high-risk donors for VVR. For the high-risk donors, 300 
      mL of water ingestion may be a simple and effective way of prevention against 
      syncopal VVR.
FAU - Ando, Shin-ichi
AU  - Ando S
AD  - Cardiology Division, Saiseikai Futsukaichi Hospital, 3-13-1 Yumachi, Chikushino 
      818-8516, Japan. shinando@ab.mbn.or.jp
FAU - Kawamura, Natsumi
AU  - Kawamura N
FAU - Matsumoto, Mari
AU  - Matsumoto M
FAU - Dan, Emi
AU  - Dan E
FAU - Takeshita, Akira
AU  - Takeshita A
FAU - Murakami, Kazuko
AU  - Murakami K
FAU - Kashiwagi, Seizaburo
AU  - Kashiwagi S
FAU - Kiyokawa, Hiroyuki
AU  - Kiyokawa H
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Transfusion
JT  - Transfusion
JID - 0417360
RN  - 059QF0KO0R (Water)
SB  - IM
MH  - Adult
MH  - *Drinking
MH  - Female
MH  - *Heart Rate
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Risk Factors
MH  - *Syncope, Vasovagal/diagnosis/physiopathology/prevention & control
MH  - Time Factors
MH  - Water/*administration & dosage
EDAT- 2009/05/06 09:00
MHDA- 2011/04/22 06:00
CRDT- 2009/05/06 09:00
PHST- 2009/05/06 09:00 [entrez]
PHST- 2009/05/06 09:00 [pubmed]
PHST- 2011/04/22 06:00 [medline]
AID - TRF02189 [pii]
AID - 10.1111/j.1537-2995.2009.02189.x [doi]
PST - ppublish
SO  - Transfusion. 2009 Aug;49(8):1630-6. doi: 10.1111/j.1537-2995.2009.02189.x.