PMID- 19420927
OWN - NLM
STAT- MEDLINE
DCOM- 20090519
LR  - 20090507
IS  - 1424-859X (Electronic)
IS  - 1424-8581 (Linking)
VI  - 124
IP  - 2
DP  - 2009
TI  - Conservation of a chromosome arm in two distantly related marsupial species.
PG  - 147-50
LID - 10.1159/000207522 [doi]
AB  - Marsupials, which diverged from eutherian mammals 150 million years ago (MYA), 
      occupy a phylogenetic position that is very valuable in genome comparisons of 
      mammal and other vertebrate species. Within the marsupials, the Australian and 
      American clades (represented by the tammar wallaby Macropus eugenii, and the 
      opossum Monodelphis domestica) diverged about 70 MYA. G-banding and chromosome 
      painting suggest that tammar wallaby chromosome 6q has homology to opossum 
      chromosome 7q. We tested this conservation by physically mapping the tammar 
      wallaby orthologs of opossum chromosome 7q genes. We isolated 28 tammar wallaby 
      BAC clones that contained orthologs of 16 opossum chromosome 7q genes. We used 
      fluorescence in situ hybridization (FISH) to show that they all mapped 
      specifically to the tammar wallaby chromosome 6q in nearly the same order as 
      their orthologs on opossum chromosome 7q. Thus this chromosome arm is 
      genetically, as well as cytologically, conserved over the 55-80 million years 
      that separate kangaroos and the opossum.
CI  - Copyright 2009 S. Karger AG, Basel.
FAU - Mohammadi, A
AU  - Mohammadi A
AD  - ARC Centre of Excellence for Kangaroo Genomics, Research School of Biological 
      Sciences, The Australian National University, Canberra, ACT, Australia. 
      Amir.Mohammadi@anu.edu.au
FAU - Delbridge, M L
AU  - Delbridge ML
FAU - Waters, P D
AU  - Waters PD
FAU - Graves, J A Marshall
AU  - Graves JA
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20090505
PL  - Switzerland
TA  - Cytogenet Genome Res
JT  - Cytogenetic and genome research
JID - 101142708
SB  - IM
MH  - Animals
MH  - Chromosomes, Mammalian/*genetics
MH  - *Conserved Sequence
MH  - Male
MH  - Marsupialia/*genetics
MH  - Physical Chromosome Mapping
EDAT- 2009/05/08 09:00
MHDA- 2009/05/20 09:00
CRDT- 2009/05/08 09:00
PHST- 2008/12/12 00:00 [accepted]
PHST- 2009/05/08 09:00 [entrez]
PHST- 2009/05/08 09:00 [pubmed]
PHST- 2009/05/20 09:00 [medline]
AID - 000207522 [pii]
AID - 10.1159/000207522 [doi]
PST - ppublish
SO  - Cytogenet Genome Res. 2009;124(2):147-50. doi: 10.1159/000207522. Epub 2009 May 
      5.