PMID- 19424318
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20130704
LR  - 20190516
IS  - 1094-4087 (Electronic)
IS  - 1094-4087 (Linking)
VI  - 9
IP  - 13
DP  - 2001 Dec 17
TI  - Analysis of nonlinear relation for skin hemoglobin imaging.
PG  - 802-12
AB  - This paper discusses the accuracy of the optical determination of the oxygenated 
      and deoxygenated hemoglobin content of human skin under the influence of a 
      melanin layer for a multi-wavelengths imager. The relation between the nonlinear 
      results by Monte Carlo simulation (MCS) and the modified Lambert Beer's law (MLB) 
      is also clarified, emphasizing the importance of the absolute values of skin 
      pigments and their influence on the mean path-length used in MLB. The fitting 
      procedure of the MCS data to the actual skin spectra is shown to obtain the 
      absolute values. It is also shown that once the proper mean path-lengths have 
      been determined, MLB can be used fairly well within an accuracy of 80% compared 
      with MCS. Images of oxygenated hemoglobin with a newly-developed fourwavelength 
      camera are presented to demonstrate the advantages of a multiwavelength system.
FAU - Kobayashi, M
AU  - Kobayashi M
FAU - Ito, Y
AU  - Ito Y
FAU - Sakauchi, N
AU  - Sakauchi N
FAU - Oda, I
AU  - Oda I
FAU - Konishi, I
AU  - Konishi I
FAU - Tsunazawa, Y
AU  - Tsunazawa Y
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Opt Express
JT  - Optics express
JID - 101137103
EDAT- 2001/12/17 00:00
MHDA- 2001/12/17 00:01
CRDT- 2009/05/09 09:00
PHST- 2009/05/09 09:00 [entrez]
PHST- 2001/12/17 00:00 [pubmed]
PHST- 2001/12/17 00:01 [medline]
AID - 66909 [pii]
AID - 10.1364/oe.9.000802 [doi]
PST - ppublish
SO  - Opt Express. 2001 Dec 17;9(13):802-12. doi: 10.1364/oe.9.000802.