PMID- 19426413
OWN - NLM
STAT- MEDLINE
DCOM- 20090825
LR  - 20220309
IS  - 1525-139X (Electronic)
IS  - 0894-0959 (Linking)
VI  - 22
IP  - 2
DP  - 2009 Mar-Apr
TI  - Modalities of continuous renal replacement therapy: technical and clinical 
      considerations.
PG  - 114-22
LID - 10.1111/j.1525-139X.2008.00549.x [doi]
AB  - Continuous renal replacement therapies (CRRT) are continuous forms of renal 
      functional replacement used to manage acute kidney injury (AKI) in the critically 
      ill patient. Depurative mechanisms include convection, diffusion, and membrane 
      adsorption utilizing high-flux highly permeable biocompatible dialysis membranes. 
      The simultaneous infusion of replacement fluid permits fluid removal without 
      intravascular volume contraction and better hemodynamic stability, metabolic 
      control to almost normal parameters, and removal of large-size toxins and 
      cytokines. Moreover, CRRT allows better long-term clearance of small and middle 
      molecules than other dialysis modalities. This article focuses on the different 
      modalities of CRRT and reviews both the basic concepts and the newest approaches 
      to the management of the critically ill patient with AKI.
FAU - Cerda, Jorge
AU  - Cerda J
AD  - Division of Nephrology, Albany Medical College and Capital District Renal 
      Physicians, 62 Hackett Boulevard, Albany, NY 12209-1718, USA. cerda@nycap.rr.com
FAU - Ronco, Claudio
AU  - Ronco C
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Semin Dial
JT  - Seminars in dialysis
JID - 8911629
RN  - 0 (Biocompatible Materials)
RN  - 0 (Membranes, Artificial)
SB  - IM
MH  - Acute Kidney Injury/*therapy
MH  - Biocompatible Materials/*standards
MH  - Equipment Design
MH  - Humans
MH  - *Membranes, Artificial
MH  - *Models, Theoretical
MH  - Renal Replacement Therapy/*instrumentation
RF  - 62
EDAT- 2009/05/12 09:00
MHDA- 2009/08/26 09:00
CRDT- 2009/05/12 09:00
PHST- 2009/05/12 09:00 [entrez]
PHST- 2009/05/12 09:00 [pubmed]
PHST- 2009/08/26 09:00 [medline]
AID - SDI549 [pii]
AID - 10.1111/j.1525-139X.2008.00549.x [doi]
PST - ppublish
SO  - Semin Dial. 2009 Mar-Apr;22(2):114-22. doi: 10.1111/j.1525-139X.2008.00549.x.