PMID- 19430834 OWN - NLM STAT- MEDLINE DCOM- 20120416 LR - 20211020 IS - 1432-2218 (Electronic) IS - 0930-2794 (Linking) VI - 23 IP - 12 DP - 2009 Dec TI - The minimal clinically important difference in the Gastrointestinal Quality-of-Life Index after cholecystectomy. PG - 2708-12 LID - 10.1007/s00464-009-0475-6 [doi] AB - BACKGROUND: The minimal clinically important difference (MCID) for the Gastrointestinal Quality of Life Index (GIQLI) is unknown, which limits its application and interpretation. This study aimed to estimate MCIDs for the GIQLI scores of patients after they had undergone cholecystectomy. METHODS: This study had 267 participants. All the participants completed the GIQLI and four anchor items, namely, "How would you describe your overall symptoms, emotions, physical functions, and social functions since your last visit?" The response options were "much worse," "somewhat worse," "same," "somewhat better" and "much better." The MCID was defined according to those who responded with "somewhat better." RESULTS: The mean age of the participants was 57.81 +/- 14.93 years, and 37.08% of the patients were women. The MCID group included 67, 78, 44, and 22 patients with MCIDs of 6.42, 6.86, 7.64 and 6.46 points respectively for scores on the symptoms, emotions, physical functions, and social functions subscales, respectively. The effect sizes of four anchors in the "somewhat better" group (0.38-0.49) exceeded those of the same group (0.25-0.38). CONCLUSIONS: This study showed that after patients had undergone cholecystectomy, the clinically significant mean changes in their scores on the GIQLI subscales for symptoms, emotions, physical functions, and social function were respectively 6.42, 6.86, 7.64, and 6.46 points. After patients have undergone cholecystectomy, the MCIDs for the GIQLI subscales can play an important role in interpretation of the scores, application of them in clinical practice, and verification of treatment effects. FAU - Shi, Hon-Yi AU - Shi HY AD - Graduate Institute of Healthcare Administration, Kaohsiung Medical University, 100, Shih-Chuan 1st Road, 807 Kaohsiung, Taiwan. FAU - Lee, King-Teh AU - Lee KT FAU - Lee, Hao-Hsien AU - Lee HH FAU - Uen, Yih-Huei AU - Uen YH FAU - Na, Hsueh-Li AU - Na HL FAU - Chao, Fang-Tse AU - Chao FT FAU - Chiu, Chong-Chi AU - Chiu CC LA - eng PT - Evaluation Study PT - Journal Article PT - Multicenter Study DEP - 20090509 PL - Germany TA - Surg Endosc JT - Surgical endoscopy JID - 8806653 SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - Cholecystectomy/*psychology/statistics & numerical data MH - Cholecystectomy, Laparoscopic/psychology/statistics & numerical data MH - Emotions MH - Female MH - Gastrointestinal Diseases/psychology MH - *Health Status Indicators MH - Humans MH - Length of Stay MH - Male MH - Middle Aged MH - Patient Satisfaction MH - Postoperative Complications/psychology MH - *Quality of Life MH - Surveys and Questionnaires MH - Treatment Outcome MH - Young Adult EDAT- 2009/05/12 09:00 MHDA- 2012/04/17 06:00 CRDT- 2009/05/12 09:00 PHST- 2008/12/24 00:00 [received] PHST- 2009/03/14 00:00 [accepted] PHST- 2009/03/11 00:00 [revised] PHST- 2009/05/12 09:00 [entrez] PHST- 2009/05/12 09:00 [pubmed] PHST- 2012/04/17 06:00 [medline] AID - 10.1007/s00464-009-0475-6 [doi] PST - ppublish SO - Surg Endosc. 2009 Dec;23(12):2708-12. doi: 10.1007/s00464-009-0475-6. Epub 2009 May 9.