PMID- 19443421 OWN - NLM STAT- MEDLINE DCOM- 20091103 LR - 20191210 IS - 1522-9645 (Electronic) IS - 0195-668X (Linking) VI - 30 IP - 14 DP - 2009 Jul TI - Quality of life assessment after percutaneous aortic valve implantation. PG - 1790-6 LID - 10.1093/eurheartj/ehp171 [doi] AB - AIMS: To assess the NYHA class and the quality of life (QoL) scores after percutaneous aortic valve implantation (PAVI) with the 18-Fr CoreValve prosthesis. METHODS AND RESULTS: From April 2007 until August 2008, 57 consecutive patients with aortic stenosis were evaluated for PAVI. Of these, 30 patients with successfully prosthesis implantation had more than 5-month follow-up. QoL assessment was realized with the SF-12v2 Health-Survey, a simple questionnaire designed for self-administration that provides easily interpretable scales for physical [physical component summary (PCS)] and mental [mental component summary (MCS)] health. The questionnaire was administered before and 5 months after PAVI. All 30 patients had a marked upgrading in haemodynamic and echocardiographic parameters (peak-to-peak gradient from 64 +/- 23 to 2 +/- 0.4; P < 0.001; aortic valve area index from 0.3 +/- 0.1 to 0.9 +/- 0.3; P < 0.001), with an improvement in New York Heart Association (NYHA) class at discharge and after 5 months. Mean pre-operative SF-12v2 scores showed a severe impairment of perceived quality of life compared with general Italian population >75 years, both for physical (PCS-baseline 28.5 vs. 37.9, P < 0.001) and mental scores (MCS-baseline 37.8 vs. 45.4, P < 0.001). After 5 months, a striking improvement in both scores (PCS 41.3-MCS 48.3; P < 0.001) was observed. CONCLUSION: Our preliminary results show a marked short-term improvement in functional status and physical and mental health in patients underwent PAVI. FAU - Ussia, Gian Paolo AU - Ussia GP AD - Division of Cardiology, Ferrarotto Hospital, University of Catania, Via Citelli 6, Catania, Italy. gpussia@hotmail.com FAU - Mule, Massimiliano AU - Mule M FAU - Barbanti, Marco AU - Barbanti M FAU - Cammalleri, Valeria AU - Cammalleri V FAU - Scarabelli, Marilena AU - Scarabelli M FAU - Imme, Sebastiano AU - Imme S FAU - Capodanno, Davide AU - Capodanno D FAU - Ciriminna, Saverio AU - Ciriminna S FAU - Tamburino, Corrado AU - Tamburino C LA - eng PT - Evaluation Study PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20090513 PL - England TA - Eur Heart J JT - European heart journal JID - 8006263 SB - IM MH - Aged, 80 and over MH - Aortic Valve/*surgery MH - Aortic Valve Stenosis/*surgery MH - Female MH - Health Surveys MH - Heart Valve Prosthesis Implantation/*psychology MH - Humans MH - Male MH - Quality of Life/*psychology MH - Surveys and Questionnaires EDAT- 2009/05/16 09:00 MHDA- 2009/11/05 06:00 CRDT- 2009/05/16 09:00 PHST- 2009/05/16 09:00 [entrez] PHST- 2009/05/16 09:00 [pubmed] PHST- 2009/11/05 06:00 [medline] AID - ehp171 [pii] AID - 10.1093/eurheartj/ehp171 [doi] PST - ppublish SO - Eur Heart J. 2009 Jul;30(14):1790-6. doi: 10.1093/eurheartj/ehp171. Epub 2009 May 13.