PMID- 19443982 OWN - NLM STAT- MEDLINE DCOM- 20090814 LR - 20190606 IS - 1349-7235 (Electronic) IS - 0918-2918 (Linking) VI - 48 IP - 10 DP - 2009 TI - Acute autonomic, sensory and motor neuropathy: successful treatment with IVIg. PG - 843-6 AB - Acute autonomic, sensory and motor neuropathy (AASMN) is a rare peripheral nerve disorder characterized by prominent dysautonomia with somatic sensory and motor impairment. Dysautonomia in AASMN is intractable even with corticosteroid therapy or plasmapheresis. Here we report a case of AASMN with severe orthostatic hypotension. Although the effectiveness of corticosteroid was insufficient, high dose intravenous immunoglobulin therapy (IVIg) was effective for not only sensorimotor symptoms but also autonomic symptoms. This is the first case of AASMN showing favorable responses to IVIg treatment, suggesting that IVIg should be considered when corticosteroid therapy or plasmapheresis is ineffective or insufficient. FAU - Ueda, Akihiro AU - Ueda A AD - Department of Neurology, Fujita Health University School of Medicine, Toyoake. FAU - Asakura, Kunihiko AU - Asakura K FAU - Mihara, Takateru AU - Mihara T FAU - Hara, Hideo AU - Hara H FAU - Ueda, Madoka AU - Ueda M FAU - Miyashita, Tadayuki AU - Miyashita T FAU - Mutoh, Tatsuro AU - Mutoh T LA - eng PT - Case Reports PT - Journal Article DEP - 20090515 PL - Japan TA - Intern Med JT - Internal medicine (Tokyo, Japan) JID - 9204241 RN - 0 (Immunoglobulins, Intravenous) RN - EC 3.4.23.15 (Renin) RN - X4W3ENH1CV (Norepinephrine) SB - IM MH - Acute Disease MH - Autonomic Nervous System Diseases/diagnosis/physiopathology/*therapy MH - Humans MH - Immunoglobulins, Intravenous/*therapeutic use MH - Male MH - Middle Aged MH - Norepinephrine/blood MH - Peripheral Nervous System Diseases/diagnosis/physiopathology/*therapy MH - Renin/blood MH - Shy-Drager Syndrome/diagnosis/physiopathology/therapy MH - Tilt-Table Test EDAT- 2009/05/16 09:00 MHDA- 2009/08/15 09:00 CRDT- 2009/05/16 09:00 PHST- 2009/05/16 09:00 [entrez] PHST- 2009/05/16 09:00 [pubmed] PHST- 2009/08/15 09:00 [medline] AID - JST.JSTAGE/internalmedicine/48.1848 [pii] AID - 10.2169/internalmedicine.48.1848 [doi] PST - ppublish SO - Intern Med. 2009;48(10):843-6. doi: 10.2169/internalmedicine.48.1848. Epub 2009 May 15.