PMID- 19454030 OWN - NLM STAT- MEDLINE DCOM- 20090702 LR - 20211020 IS - 1742-4690 (Electronic) IS - 1742-4690 (Linking) VI - 6 DP - 2009 May 19 TI - Memories of John N. Brady: scientist, mentor and friend. PG - 48 LID - 10.1186/1742-4690-6-48 [doi] AB - Friends and colleagues remember John N. Brady, Ph.D., Chief of the Virus Tumor Biology Section of the Laboratory of Cellular Oncology, who died much too young at the age of 57 on April 27, 2009 of colon cancer. John grew up in Illinois and received his Ph.D. with Dr. Richard Consigli at Kansas State University studying the molecular structure of polyomavirus. In 1984 John came to the National Institutes of Health as a Staff Fellow in the laboratory of Dr. Norman Salzman, Laboratory of Biology of Viruses NIAID, where he was among the first to analyze SV40 transcription using in vitro transcription systems and to analyze regulatory sequences for SV40 late transcription. He then trained with Dr. George Khoury in the Laboratory of Molecular Virology NCI, where he identified SV40 T-antigen as a transcriptional activator protein. His research interests grew to focus on the human retroviruses: human T-cell lymphotropic virus type I (HTLV-I) and human immunodeficiency virus (HIV), analyzing how interactions between these viruses and the host cell influence viral gene regulation, viral pathogenesis and viral transformation. His research also impacted the fields of eukaryotic gene regulation and tumor suppressor proteins. John is survived by his wife, Laraine, and two sons, Matt and Kevin. FAU - Pise-Masison, Cynthia A AU - Pise-Masison CA AD - Laboratory of Cellular Oncology, Center for Cancer Research, National Cancer Institute, National Institute of Health, Bethesda, Maryland 20892, USA. masisonc@dce41.nci.nih.gov FAU - Marriott, Susan J AU - Marriott SJ LA - eng GR - P30 AI036211/AI/NIAID NIH HHS/United States PT - Biography PT - Editorial PT - Historical Article DEP - 20090519 PL - England TA - Retrovirology JT - Retrovirology JID - 101216893 SB - IM MH - History, 20th Century MH - History, 21st Century MH - Humans MH - United States MH - Virology/*history PS - Brady JN FPS - Brady, John N PMC - PMC2693500 EDAT- 2009/05/21 09:00 MHDA- 2009/07/03 09:00 PMCR- 2009/05/19 CRDT- 2009/05/21 09:00 PHST- 2009/05/06 00:00 [received] PHST- 2009/05/19 00:00 [accepted] PHST- 2009/05/21 09:00 [entrez] PHST- 2009/05/21 09:00 [pubmed] PHST- 2009/07/03 09:00 [medline] PHST- 2009/05/19 00:00 [pmc-release] AID - 1742-4690-6-48 [pii] AID - 10.1186/1742-4690-6-48 [doi] PST - epublish SO - Retrovirology. 2009 May 19;6:48. doi: 10.1186/1742-4690-6-48.