PMID- 19459202
OWN - NLM
STAT- MEDLINE
DCOM- 20090908
LR  - 20091119
IS  - 1545-5017 (Electronic)
IS  - 1545-5009 (Linking)
VI  - 53
IP  - 4
DP  - 2009 Oct
TI  - Transient neonatal acquired von Willebrand syndrome due to transplacental 
      transfer of maternal monoclonal antibodies.
PG  - 655-7
LID - 10.1002/pbc.22084 [doi]
AB  - Although typically a disorder of adults, acquired von Willebrand syndrome (AVWS) 
      is increasingly being recognized in the pediatric population in association with 
      congenital cardiac diseases, certain neoplasia, and hypothyroidism. 
      Transplacental transfer of maternal immunoglobulin G (IgG) antibodies as a cause 
      of neonatal disorders in infants born to mothers with autoimmune conditions has 
      been reported. We describe the diagnosis and peripartum clinical management of 
      AVWS due to monoclonal gammopathy of undetermined significance (MGUS) and the 
      first reported case of transient neonatal AVWS due to transplacental transfer of 
      maternal IgG antibodies.
FAU - Nageswara Rao, Amulya A
AU  - Nageswara Rao AA
AD  - Division of Pediatric Hematology/Oncology, Mayo Clinic, Rochester, Minnesota 
      55905, USA.
FAU - Rodriguez, Vilmarie
AU  - Rodriguez V
FAU - Long, Margaret E
AU  - Long ME
FAU - Winters, Jeffrey L
AU  - Winters JL
FAU - Nichols, William L
AU  - Nichols WL
FAU - Pruthi, Rajiv K
AU  - Pruthi RK
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Pediatr Blood Cancer
JT  - Pediatric blood & cancer
JID - 101186624
RN  - 0 (Antibodies, Monoclonal)
RN  - 0 (Immunoglobulin G)
SB  - IM
MH  - Adult
MH  - Antibodies, Monoclonal/*metabolism
MH  - Female
MH  - Humans
MH  - Immunoglobulin G/metabolism
MH  - Infant, Newborn
MH  - *Maternal-Fetal Exchange
MH  - Pregnancy
MH  - von Willebrand Diseases/*etiology
EDAT- 2009/05/22 09:00
MHDA- 2009/09/09 06:00
CRDT- 2009/05/22 09:00
PHST- 2009/05/22 09:00 [entrez]
PHST- 2009/05/22 09:00 [pubmed]
PHST- 2009/09/09 06:00 [medline]
AID - 10.1002/pbc.22084 [doi]
PST - ppublish
SO  - Pediatr Blood Cancer. 2009 Oct;53(4):655-7. doi: 10.1002/pbc.22084.