PMID- 19470862
OWN - NLM
STAT- MEDLINE
DCOM- 20090807
LR  - 20161125
IS  - 0268-3555 (Print)
IS  - 0268-3555 (Linking)
VI  - 24
IP  - 3
DP  - 2009 Jun
TI  - Transient adverse events positively associated with patent foramen ovale after 
      ultrasound-guided foam sclerotherapy.
PG  - 114-9
LID - 10.1258/phleb.2008.008060 [doi]
AB  - OBJECTIVES: To prospectively study the association between patent foramen ovale 
      (PFO) detected by contrast transcranial Doppler (cTCD) and adverse events (AEs) 
      reported by patients after ultrasound-guided foam sclerotherapy (UGFS) for the 
      treatment of varicose veins. METHODS: All patients reporting AEs after UGFS were 
      studied using cTCD directed at the middle cerebral artery to determine the 
      Spencer grading score by counting high-intensity transient signals. Agitated 
      saline was used as the contrast medium. The Spencer grading score determined the 
      presence or absence of PFO. All patients undergoing UGFS received follow-up phone 
      calls within 24 hours and again two weeks after the procedure. RESULTS: Of the 
      3259 patients who underwent UGFS, AEs were reported by seven (0.21%) patients at 
      their first session. These included visual disturbance, migraine and chest 
      discomfort. Five (71.4%) of these seven patients tested positive for PFO by cTCD. 
      The two-week follow-up confirmed no permanent symptoms. Published studies show 
      high sensitivity and specificity for cTCD when compared with contrast 
      transesophageal echocardiography (cTEE). CONCLUSIONS: The overall rate of AEs 
      reported is consistent with published results. The presence of a PFO was detected 
      in most patients reporting AEs after undergoing UGFS. While PFO screening with 
      high sensitivity and specificity can be performed efficiently in the clinic 
      setting, based on the literature, further investigation is warranted.
FAU - Raymond-Martimbeau, Pauline
AU  - Raymond-Martimbeau P
AD  - Dallas Non-Invasive Vascular Laboratory, Dallas, TX, USA. pmartimbo@aol.com
LA  - eng
PT  - Journal Article
PL  - England
TA  - Phlebology
JT  - Phlebology
JID - 9012921
SB  - IM
MH  - Adult
MH  - Aged
MH  - Chest Pain/etiology
MH  - Echocardiography, Transesophageal
MH  - Female
MH  - Follow-Up Studies
MH  - Foramen Ovale, Patent/diagnostic imaging/*epidemiology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Migraine Disorders/etiology
MH  - Prospective Studies
MH  - Sclerotherapy/*adverse effects/*statistics & numerical data
MH  - Sensitivity and Specificity
MH  - Ultrasonography, Doppler, Transcranial
MH  - Varicose Veins/*epidemiology/*therapy
MH  - Vision Disorders/etiology
MH  - Young Adult
EDAT- 2009/05/28 09:00
MHDA- 2009/08/08 09:00
CRDT- 2009/05/28 09:00
PHST- 2009/05/28 09:00 [entrez]
PHST- 2009/05/28 09:00 [pubmed]
PHST- 2009/08/08 09:00 [medline]
AID - 24/3/114 [pii]
AID - 10.1258/phleb.2008.008060 [doi]
PST - ppublish
SO  - Phlebology. 2009 Jun;24(3):114-9. doi: 10.1258/phleb.2008.008060.