PMID- 19471496
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20121002
LR  - 20220318
IS  - 1094-4087 (Electronic)
IS  - 1094-4087 (Linking)
VI  - 11
IP  - 26
DP  - 2003 Dec 29
TI  - High-speed spectral-domain optical coherence tomography at 1.3 mum wavelength.
PG  - 3598-604
AB  - We demonstrate a high-speed spectral domain optical coherence tomography (SD-OCT) 
      system capable of acquiring individual axial scans in 24.4 micros at a rate of 
      19,000 axial scans per second, using an InGaAs line scan camera and broadband 
      light source centered at 1.31microm. Sensitivity of >105 dB over a 2-mm depth 
      range was obtained with a free-space axial resolution of 12-14 microm, in 
      agreement with our signal-to-noise ratio predictions. Images of human tissue 
      obtained in vivo with SD-OCT show similar penetration depths to those obtained 
      with state-of-the-art time domain OCT despite the ten-fold higher image 
      acquisition speed. These results demonstrate the potential of 1.3 microm SD-OCT 
      for high-speed and high-sensitivity imaging in patients.
FAU - Yun, S
AU  - Yun S
FAU - Tearney, G
AU  - Tearney G
FAU - Bouma, B
AU  - Bouma B
FAU - Park, B
AU  - Park B
FAU - de Boer, Johannes
AU  - de Boer J
LA  - eng
GR  - R01 CA103769/CA/NCI NIH HHS/United States
GR  - R01 CA103769-02/CA/NCI NIH HHS/United States
GR  - R01 RR019768/RR/NCRR NIH HHS/United States
GR  - R01 RR019768-02/RR/NCRR NIH HHS/United States
PT  - Journal Article
PL  - United States
TA  - Opt Express
JT  - Optics express
JID - 101137103
PMC - PMC2713046
MID - NIHMS120316
EDAT- 2003/12/29 00:00
MHDA- 2003/12/29 00:01
PMCR- 2009/07/20
CRDT- 2009/05/28 09:00
PHST- 2009/05/28 09:00 [entrez]
PHST- 2003/12/29 00:00 [pubmed]
PHST- 2003/12/29 00:01 [medline]
PHST- 2009/07/20 00:00 [pmc-release]
AID - 78225 [pii]
AID - 10.1364/oe.11.003598 [doi]
PST - ppublish
SO  - Opt Express. 2003 Dec 29;11(26):3598-604. doi: 10.1364/oe.11.003598.