PMID- 19472903
OWN - NLM
STAT- MEDLINE
DCOM- 20090805
LR  - 20090528
IS  - 1009-3591 (Print)
IS  - 1009-3591 (Linking)
VI  - 15
IP  - 4
DP  - 2009 Apr
TI  - [Expression of estrogen receptor beta in benign prostatic hyperplasia complicated 
      by chronic prostatitis].
PG  - 314-7
AB  - OBJECTIVE: To observe the expression of estrogen receptor-beta (ERbeta) in benign 
      prostatic hyperplasia (BPH) complicated by chronic prostatitis, and to evaluate 
      the correlation of chronic prostatitis with ERbeta expression. METHODS: 
      Histological sections of prostate tissues were obtained from 60 BPH patients 
      complicated by chronic prostatitis and divided into Group 1 (Grade 1), 2 (Grade 
      2) and 3 (Grade 3) according to the scores on the inflammation of the prostate 
      tissues using the four-point scale designed by Irani et al. The expression of 
      ERbeta was determined by the immunohistochemical method. RESULTS: There were 24 
      cases (40%) in Group 1, 21 (35%) in Group 2 and 15 (25%) in Group 3, with no 
      statistically significant differences in age and prostate volume among the three 
      groups (P > 0.05). The expression of ERbeta was significantly decreased in Groups 
      2 and 3 as compared with Group 1 (P < 0.01). CONCLUSION: The expression of ERbeta 
      is reduced with increased scores on the inflammation of the prostate tissues in 
      BPH patients, and the decreased ERbeta expression may be associated with the 
      inflammatory stimulation of prostatitis.
FAU - Yang, Guo-Qing
AU  - Yang GQ
AD  - Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 
      430071, China.
FAU - Li, Shi-Wen
AU  - Li SW
FAU - Zheng, Hang
AU  - Zheng H
FAU - Zhang, Wei-Bing
AU  - Zhang WB
FAU - Hu, Wan-Li
AU  - Hu WL
FAU - Zheng, Xin-Min
AU  - Zheng XM
LA  - chi
PT  - English Abstract
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Zhonghua Nan Ke Xue
JT  - Zhonghua nan ke xue = National journal of andrology
JID - 101093592
RN  - 0 (Estrogen Receptor beta)
SB  - IM
MH  - Aged
MH  - Chronic Disease
MH  - Estrogen Receptor beta/*biosynthesis
MH  - Humans
MH  - Male
MH  - Prostatic Hyperplasia/complications/*metabolism/pathology
MH  - Prostatitis/complications/*metabolism/pathology
EDAT- 2009/05/29 09:00
MHDA- 2009/08/06 09:00
CRDT- 2009/05/29 09:00
PHST- 2009/05/29 09:00 [entrez]
PHST- 2009/05/29 09:00 [pubmed]
PHST- 2009/08/06 09:00 [medline]
PST - ppublish
SO  - Zhonghua Nan Ke Xue. 2009 Apr;15(4):314-7.