PMID- 19477402
OWN - NLM
STAT- MEDLINE
DCOM- 20090922
LR  - 20090529
IS  - 1532-8414 (Electronic)
IS  - 1071-9164 (Linking)
VI  - 15
IP  - 5
DP  - 2009 Jun
TI  - Delayed enhancement on cardiac magnetic resonance and clinical, morphological, 
      and electrocardiographical features in hypertrophic cardiomyopathy.
PG  - 419-27
LID - 10.1016/j.cardfail.2008.11.014 [doi]
AB  - BACKGROUND: The clinical, morphological, and electrocardiographical relevance of 
      delayed enhancement (DE) in cardiac magnetic resonance (CMR) was studied in 
      patients with hypertrophic cardiomyopathy (HCM). METHODS AND RESULTS: A total of 
      56 patients underwent both gadolinium-enhanced CMR and 12-lead electrocardiogram. 
      The CMR demonstrated DE at the left ventricular (LV) wall in 39 patients. The 
      patients with DE included more cases with dilated phase of HCM, higher New York 
      Heart Association (NYHA) classes and incidence of ventricular tachyarrhythmias 
      (VT), lower LV ejection fraction (LVEF) and mean LV wall thickness (WT), and a 
      larger ratio of maximum to minimum LVWT. The QRS duration was prolonged and the 
      QRS axis deviated toward left with increases in the DE volume (r = 0.58 and r = 
      0.41, P < .01). Abnormal Q waves were present in 5 patients and the location 
      coincided with the DE segments in 4 patients, but the concordance was not 
      significant. The amplitude of T waves correlated with the ratio of the apex to 
      basal LVWT (r = 0.38, P < .01) and was more negative in cases with DE at the 
      apex. CONCLUSIONS: In HCM, the DE was associated with higher NYHA classes and 
      prevalence of VT, impaired global LV function and asymmetrical hypertrophy, and 
      conduction disturbance, abnormal Q waves, and giant negative T waves.
FAU - Satoh, Hiroshi
AU  - Satoh H
AD  - Division of Cardiology, Internal Medicine III, Hamamatsu University School of 
      Medicine, Higashi-ku, Hamamatsu, Japan. satoh36@hama-med.ac.jp
FAU - Matoh, Fumitaka
AU  - Matoh F
FAU - Shiraki, Katsunori
AU  - Shiraki K
FAU - Saitoh, Takeji
AU  - Saitoh T
FAU - Odagiri, Keiichi
AU  - Odagiri K
FAU - Saotome, Masao
AU  - Saotome M
FAU - Urushida, Tsuyoshi
AU  - Urushida T
FAU - Katoh, Hideki
AU  - Katoh H
FAU - Takehara, Yasuo
AU  - Takehara Y
FAU - Sakahara, Harumi
AU  - Sakahara H
FAU - Hayashi, Hideharu
AU  - Hayashi H
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20090120
PL  - United States
TA  - J Card Fail
JT  - Journal of cardiac failure
JID - 9442138
SB  - IM
MH  - Cardiomyopathy, Hypertrophic/*diagnosis/physiopathology
MH  - Electrocardiography/*methods
MH  - Female
MH  - Follow-Up Studies
MH  - Heart Ventricles/*pathology/physiopathology
MH  - Humans
MH  - Image Enhancement/*methods
MH  - Magnetic Resonance Imaging/*methods
MH  - Male
MH  - Middle Aged
MH  - Reproducibility of Results
MH  - Retrospective Studies
MH  - Ventricular Function, Left/*physiology
EDAT- 2009/05/30 09:00
MHDA- 2009/09/23 06:00
CRDT- 2009/05/30 09:00
PHST- 2008/05/28 00:00 [received]
PHST- 2008/10/09 00:00 [revised]
PHST- 2008/11/26 00:00 [accepted]
PHST- 2009/05/30 09:00 [entrez]
PHST- 2009/05/30 09:00 [pubmed]
PHST- 2009/09/23 06:00 [medline]
AID - S1071-9164(08)01098-1 [pii]
AID - 10.1016/j.cardfail.2008.11.014 [doi]
PST - ppublish
SO  - J Card Fail. 2009 Jun;15(5):419-27. doi: 10.1016/j.cardfail.2008.11.014. Epub 
      2009 Jan 20.