PMID- 19482414
OWN - NLM
STAT- MEDLINE
DCOM- 20110209
LR  - 20220408
IS  - 1873-7560 (Electronic)
IS  - 0302-2838 (Linking)
VI  - 57
IP  - 4
DP  - 2010 Apr
TI  - Plasma vaporisation of the prostate: initial clinical results.
PG  - 693-7
LID - 10.1016/j.eururo.2009.05.031 [doi]
AB  - BACKGROUND: Laser vaporisation of the prostate has had a considerable impact in 
      recent years. In an attempt to achieve tissue vaporisation with bipolar 
      high-frequency generators, plasma vaporisation was recently introduced. 
      OBJECTIVE: To provide the first clinical information on bipolar plasma 
      vaporisation of the prostate for patients with lower urinary tract symptoms 
      (LUTS) due to bladder outlet obstruction (BOO). DESIGN, SETTING, AND 
      PARTICIPANTS: Thirty patients were included in this prospective bicentre study. 
      INTERVENTION: All patients underwent bipolar plasma vaporisation with a novel 
      electrode (Olympus Winter & Ibe GmbH, Hamburg, Germany). MEASUREMENTS: 
      International Prostate Symptom Score (IPSS), bother score, maximum flow rate 
      (Q(max)), and postvoid residual were evaluated at baseline and at the time of 
      discharge as well as at 1, 3, and 6 mo after the intervention. RESULTS AND 
      LIMITATIONS: Mean preoperative prostate volume was 59+/-32 ml (range: 30-170), and 
      mean operating time was 61+/-26 min (range: 20-140). Besides one reoperation 
      (conventional transurethral prostatectomy) due to persistent obstruction, no 
      major complication occurred intra- or postoperatively and no blood transfusion 
      was required. Catheterisation time averaged 41+/-35 h (range: 18-192). Transient 
      mild to moderate dysuria was noted in four patients (13%). At 1, 3, and 6 mo, 
      Q(max) increased from 6.6+/-2.7 ml/s preoperative to 17.3+/-4.7 ml/s (p<0.01), 
      18.5+/-4.6 ml/s (p<0.01), and 18.1+/-5.0 ml/s (p<0.01), respectively. The IPSS 
      decreased from 20.8+/-3.6 to 10.4+/-3.5 (p<0.01), 8.2+/-2.9 (p<0.01), and 8.1+/-3.1 
      (p<0.01), respectively. These data represent a small nonrandomised study cohort 
      with limited follow-up. CONCLUSIONS: Our initial experience indicates that 
      bipolar plasma vaporisation might be a safe and effective treatment option for 
      patients with LUTS due to BOO. To define the potential role of this novel 
      technique, randomised trials with longer follow-up are mandatory.
CI  - Copyright (c) 2009 European Association of Urology. Published by Elsevier B.V. All 
      rights reserved.
FAU - Reich, Oliver
AU  - Reich O
AD  - Department of Urology, University Hospital Munich Grosshadern, Ludwig Maximilians 
      University, D 81377 Munich, Germany. oreich@med.uni-muenchen.de
FAU - Schlenker, Boris
AU  - Schlenker B
FAU - Gratzke, Christian
AU  - Gratzke C
FAU - Tilki, Derya
AU  - Tilki D
FAU - Riecken, Malte
AU  - Riecken M
FAU - Stief, Christian
AU  - Stief C
FAU - Seitz, Michael
AU  - Seitz M
FAU - Bachmann, Alexander
AU  - Bachmann A
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
DEP - 20090526
PL  - Switzerland
TA  - Eur Urol
JT  - European urology
JID - 7512719
SB  - IM
CIN - Eur Urol. 2010 Apr;57(4):697-8. PMID: 19482413
MH  - Aged
MH  - Aged, 80 and over
MH  - Dysuria/etiology
MH  - Electrosurgery/adverse effects/*methods
MH  - Germany
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Prospective Studies
MH  - Prostatic Hyperplasia/complications/physiopathology/*surgery
MH  - Reoperation
MH  - Severity of Illness Index
MH  - Switzerland
MH  - Time Factors
MH  - Transurethral Resection of Prostate
MH  - Treatment Outcome
MH  - Urinary Bladder Neck Obstruction/etiology/physiopathology/*surgery
MH  - Urinary Catheterization
MH  - Urodynamics
MH  - Volatilization
EDAT- 2009/06/02 09:00
MHDA- 2011/02/10 06:00
CRDT- 2009/06/02 09:00
PHST- 2009/01/24 00:00 [received]
PHST- 2009/05/12 00:00 [accepted]
PHST- 2009/06/02 09:00 [entrez]
PHST- 2009/06/02 09:00 [pubmed]
PHST- 2011/02/10 06:00 [medline]
AID - S0302-2838(09)00541-7 [pii]
AID - 10.1016/j.eururo.2009.05.031 [doi]
PST - ppublish
SO  - Eur Urol. 2010 Apr;57(4):693-7. doi: 10.1016/j.eururo.2009.05.031. Epub 2009 May 
      26.