PMID- 19487257
OWN - NLM
STAT- MEDLINE
DCOM- 20090930
LR  - 20231213
IS  - 1528-0020 (Electronic)
IS  - 0006-4971 (Print)
IS  - 0006-4971 (Linking)
VI  - 114
IP  - 8
DP  - 2009 Aug 20
TI  - Mislabeled units of umbilical cord blood detected by a quality assurance program 
      at the transplantation center.
PG  - 1684-8
LID - 10.1182/blood-2009-02-205047 [doi]
AB  - We instituted procedures to check the identity of cord blood unit provided for 
      transplantation by carrying out ABO and human leukocyte antigen (HLA) typing of 
      the thawed units before transplantation. ABO typing is done using standard 
      techniques. Rapid HLA class I serology is with monoclonal antibody trays (One 
      Lambda Inc) using standard incubations. One mislabeled umbilical cord blood (UCB) 
      unit was detected on the day of intended transplantation by repeat ABO typing of 
      the thawed unit at our transplantation center. Because ABO typing will not detect 
      all labeling errors, the rapid serologic class I HLA typing procedure was done on 
      thawed units just before transplantation for all units without an attached 
      segment. This procedure identified a second mislabeled unit. In a 6-year period, 
      2 of 871 (0.2%) cord blood units sent to us for transplantation were mislabeled 
      and potentially would have been transplanted incorrectly. This error rate of 1 
      per 249 (0.4%) patients could have potentially devastating consequences.
FAU - McCullough, Jeffrey
AU  - McCullough J
AD  - Department of Laboratory Medicine and Pathology, University of Minnesota, 
      Minneapolis, MN 55455, USA. mccul001@umn.edu
FAU - McKenna, David
AU  - McKenna D
FAU - Kadidlo, Diane
AU  - Kadidlo D
FAU - Maurer, David
AU  - Maurer D
FAU - Noreen, Harriett J
AU  - Noreen HJ
FAU - French, Kathy
AU  - French K
FAU - Brunstein, Claudio
AU  - Brunstein C
FAU - Wagner, John E
AU  - Wagner JE
LA  - eng
GR  - P01 CA065493/CA/NCI NIH HHS/United States
GR  - P01 CA65493/CA/NCI NIH HHS/United States
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
DEP - 20090601
PL  - United States
TA  - Blood
JT  - Blood
JID - 7603509
SB  - IM
CIN - Blood. 2009 Aug 20;114(8):1459-60. PMID: 19696210
MH  - Adolescent
MH  - Blood Banks/organization & administration/*standards
MH  - Blood Grouping and Crossmatching
MH  - Blood Transfusion/*standards
MH  - Efficiency, Organizational
MH  - Female
MH  - *Fetal Blood/transplantation
MH  - Humans
MH  - Male
MH  - Medical Errors/prevention & control
MH  - Middle Aged
MH  - Product Labeling/*standards
MH  - Quality Control
MH  - Blood Banking/methods
PMC - PMC2731643
EDAT- 2009/06/03 09:00
MHDA- 2009/10/01 06:00
PMCR- 2010/08/20
CRDT- 2009/06/03 09:00
PHST- 2009/06/03 09:00 [entrez]
PHST- 2009/06/03 09:00 [pubmed]
PHST- 2009/10/01 06:00 [medline]
PHST- 2010/08/20 00:00 [pmc-release]
AID - S0006-4971(20)37195-0 [pii]
AID - 2009/205047 [pii]
AID - 10.1182/blood-2009-02-205047 [doi]
PST - ppublish
SO  - Blood. 2009 Aug 20;114(8):1684-8. doi: 10.1182/blood-2009-02-205047. Epub 2009 
      Jun 1.