PMID- 19493235
OWN - NLM
STAT- MEDLINE
DCOM- 20090810
LR  - 20111117
IS  - 1399-0039 (Electronic)
IS  - 0001-2815 (Linking)
VI  - 73
IP  - 6
DP  - 2009 Jun
TI  - Further evidence of an Amerindian contribution to the Polynesian gene pool on 
      Easter Island.
PG  - 582-5
LID - 10.1111/j.1399-0039.2009.01233.x [doi]
AB  - Available evidence suggests a Polynesian origin of the Easter Island population. 
      We recently found that some native Easter Islanders also carried some common 
      American Indian (Amerindian) human leukocyte antigen (HLA) alleles, which 
      probably were introduced before Europeans discovered the island in 1722. In this 
      study, we report molecular genetic investigations of 21 other selected native 
      Easter Islanders. Analysis of mitochondrial DNA and Y chromosome markers showed 
      no traces of an Amerindian contribution. However, high-resolution genomic HLA 
      typing showed that two individuals carried some other common Amerindian HLA 
      alleles, different from those found in our previous investigations. The new data 
      support our previous evidence of an Amerindian contribution to the gene pool on 
      Easter Island.
FAU - Thorsby, E
AU  - Thorsby E
AD  - Institute of Immunology, Rikshospitalet University Hospital and University of 
      Oslo, Oslo, Norway. erik.thorsby@medisin.uio.no
FAU - Flam, S T
AU  - Flam ST
FAU - Woldseth, B
AU  - Woldseth B
FAU - Dupuy, B M
AU  - Dupuy BM
FAU - Sanchez-Mazas, A
AU  - Sanchez-Mazas A
FAU - Fernandez-Vina, M A
AU  - Fernandez-Vina MA
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Tissue Antigens
JT  - Tissue antigens
JID - 0331072
RN  - 0 (HLA Antigens)
RN  - 0 (HLA-A Antigens)
RN  - 0 (HLA-B Antigens)
RN  - 0 (HLA-C Antigens)
RN  - 0 (HLA-DQ Antigens)
RN  - 0 (HLA-DQ alpha-Chains)
RN  - 0 (HLA-DQA1 antigen)
RN  - 0 (HLA-DR Antigens)
RN  - 0 (HLA-DRB1 Chains)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Gene Frequency
MH  - *Gene Pool
MH  - Genetics, Population
MH  - HLA Antigens/*genetics
MH  - HLA-A Antigens/genetics
MH  - HLA-B Antigens/genetics
MH  - HLA-C Antigens/genetics
MH  - HLA-DQ Antigens/genetics
MH  - HLA-DQ alpha-Chains
MH  - HLA-DR Antigens/genetics
MH  - HLA-DRB1 Chains
MH  - Haplotypes/genetics
MH  - Humans
MH  - Indians, South American/*genetics
MH  - Middle Aged
MH  - Polynesia
EDAT- 2009/06/06 09:00
MHDA- 2009/08/11 09:00
CRDT- 2009/06/05 09:00
PHST- 2009/06/05 09:00 [entrez]
PHST- 2009/06/06 09:00 [pubmed]
PHST- 2009/08/11 09:00 [medline]
AID - TAN1233 [pii]
AID - 10.1111/j.1399-0039.2009.01233.x [doi]
PST - ppublish
SO  - Tissue Antigens. 2009 Jun;73(6):582-5. doi: 10.1111/j.1399-0039.2009.01233.x.