PMID- 19496969
OWN - NLM
STAT- MEDLINE
DCOM- 20091124
LR  - 20151119
IS  - 1399-3038 (Electronic)
IS  - 0905-6157 (Linking)
VI  - 20
IP  - 6
DP  - 2009 Sep
TI  - Increase of inflammatory markers after indoor renovation activities: the LISA 
      birth cohort study.
PG  - 563-70
LID - 10.1111/j.1399-3038.2008.00819.x [doi]
AB  - There is concern about indoor air quality as a possible cause for health 
      impairment. Exposure to indoor renovation activities has been shown to be 
      associated with airway symptoms and allergic manifestations in children. The aim 
      of this study is to analyse immune markers responsible for disease development in 
      relation to renovation activities. Within the LISAplus (Life style Immune System 
      Allergy) birth cohort study, blood samples of 6-yr-old children were analysed for 
      concentration of the inflammatory markers interleukin (IL)-8, IL-6, tumour 
      necrosis factor-alpha, MCP-1 and IL-10. Data on indoor renovation activities 
      (painting, flooring, new furniture) were assessed with a questionnaire filled in 
      by the parents. Data on cytokine blood concentrations and exposure variables were 
      available for 250 children. Increased levels of IL-8 and MCP-1 in children's 
      blood were related to renovation activities. In particular, new floor covering 
      was associated with increased inflammatory markers. Among floor covering 
      materials only wall-to-wall carpets were associated with elevated IL-8 and 
      Monocyte Chemoattractant Protein-1 (MCP-1) levels. No association between the 
      single renovation activities painting and furnishing and blood concentration of 
      inflammatory markers has been found. Our data shows that IL-8 and MCP-1 may be 
      suitable markers for monitoring inflammatory reactions in relation with 
      renovation activities. Among renovation activities floor covering seems to induce 
      the strongest inflammatory reactions.
FAU - Herberth, Gunda
AU  - Herberth G
AD  - UFZ - Helmholtz Centre for Environmental Research Leipzig, Department of 
      Environmental Immunology, 04318 Leipzig, Germany. gunda.herberth@ufz.de
FAU - Gubelt, Reinhild
AU  - Gubelt R
FAU - Roder, Stefan
AU  - Roder S
FAU - Kramer, Ursula
AU  - Kramer U
FAU - Schins, Roel P F
AU  - Schins RP
FAU - Diez, Ulrike
AU  - Diez U
FAU - Borte, Michael
AU  - Borte M
FAU - Heinrich, Joachim
AU  - Heinrich J
FAU - Wichmann, H-Erich
AU  - Wichmann HE
FAU - Herbarth, Olf
AU  - Herbarth O
FAU - Lehmann, Irina
AU  - Lehmann I
CN  - LISAplus study group
LA  - eng
PT  - Journal Article
DEP - 20090531
PL  - England
TA  - Pediatr Allergy Immunol
JT  - Pediatric allergy and immunology : official publication of the European Society 
      of Pediatric Allergy and Immunology
JID - 9106718
RN  - 0 (Biomarkers)
RN  - 0 (CCL2 protein, human)
RN  - 0 (Chemokine CCL2)
RN  - 0 (Cytokines)
RN  - 0 (Interleukin-8)
SB  - IM
MH  - Air Pollution, Indoor/*adverse effects
MH  - Biomarkers/*blood
MH  - Chemokine CCL2/blood
MH  - Child
MH  - Child, Preschool
MH  - Cohort Studies
MH  - Cytokines/*blood
MH  - *Environmental Exposure
MH  - Female
MH  - *Floors and Floorcoverings
MH  - Humans
MH  - Inflammation/immunology
MH  - Interleukin-8/blood
MH  - Male
MH  - Residence Characteristics
MH  - Surveys and Questionnaires
FIR - Wichmann, H E
IR  - Wichmann HE
FIR - Heinrich, J
IR  - Heinrich J
FIR - Bolte, G
IR  - Bolte G
FIR - Belcredi, P
IR  - Belcredi P
FIR - Jacob, B
IR  - Jacob B
FIR - Schoetzau, A
IR  - Schoetzau A
FIR - Mosetter, M
IR  - Mosetter M
FIR - Schindler, J
IR  - Schindler J
FIR - Hohnke, A
IR  - Hohnke A
FIR - Franke, K
IR  - Franke K
FIR - Laubereau, B
IR  - Laubereau B
FIR - Sausenthaler, S
IR  - Sausenthaler S
FIR - Thaqi, A
IR  - Thaqi A
FIR - Zirngibl, A
IR  - Zirngibl A
FIR - Zutavern, A
IR  - Zutavern A
FIR - Borte, M
IR  - Borte M
FIR - Schulz, R
IR  - Schulz R
FIR - Sierig, G
IR  - Sierig G
FIR - Mirow, K
IR  - Mirow K
FIR - Gebauer, C
IR  - Gebauer C
FIR - Schulze, B
IR  - Schulze B
FIR - Borte, M
IR  - Borte M
FIR - Diez, U
IR  - Diez U
FIR - Straub, S
IR  - Straub S
FIR - Lehmann, I
IR  - Lehmann I
FIR - Sack, U
IR  - Sack U
FIR - von Berg, A
IR  - von Berg A
FIR - Scholten, C
IR  - Scholten C
FIR - Bollrath, C
IR  - Bollrath C
FIR - Gross, I
IR  - Gross I
FIR - Mollemann, M
IR  - Mollemann M
FIR - Schaaf, B
IR  - Schaaf B
FIR - Herbarth, O
IR  - Herbarth O
FIR - Bauer, M
IR  - Bauer M
FIR - Franck, U
IR  - Franck U
FIR - Graebsch, C
IR  - Graebsch C
FIR - Mueller, A
IR  - Mueller A
FIR - Rehwagen, M
IR  - Rehwagen M
FIR - Richter, M
IR  - Richter M
FIR - Roeder, S
IR  - Roeder S
FIR - Rolle-Kampczyk, U
IR  - Rolle-Kampczyk U
FIR - Schlink, U
IR  - Schlink U
FIR - Albrecht, S
IR  - Albrecht S
FIR - Jorks, A
IR  - Jorks A
FIR - Lehmann, I
IR  - Lehmann I
FIR - Herberth, G
IR  - Herberth G
FIR - Daegelmann, C
IR  - Daegelmann C
FIR - Weiss, M
IR  - Weiss M
FIR - Albert, M
IR  - Albert M
FIR - Fahlbusch, B
IR  - Fahlbusch B
FIR - Bischof, W
IR  - Bischof W
FIR - Koch, A
IR  - Koch A
FIR - Kramer, U
IR  - Kramer U
FIR - Link, E
IR  - Link E
FIR - Ranft, U
IR  - Ranft U
FIR - Schins, R
IR  - Schins R
FIR - Sugiri, D
IR  - Sugiri D
FIR - Bauer, C P
IR  - Bauer CP
FIR - Brockow, I
IR  - Brockow I
FIR - Grubl, A
IR  - Grubl A
FIR - Ring, J
IR  - Ring J
FIR - Grosch, J
IR  - Grosch J
FIR - Darsow, U
IR  - Darsow U
FIR - Weidinger, S
IR  - Weidinger S
FIR - Behrendt, H
IR  - Behrendt H
FIR - Kasche, A
IR  - Kasche A
FIR - Buters, J
IR  - Buters J
FIR - Traidl-Hoffmann, C
IR  - Traidl-Hoffmann C
FIR - Krauss-Etschmann, S
IR  - Krauss-Etschmann S
FIR - Schafer, T
IR  - Schafer T
EDAT- 2009/06/06 09:00
MHDA- 2009/12/16 06:00
CRDT- 2009/06/06 09:00
PHST- 2009/06/06 09:00 [entrez]
PHST- 2009/06/06 09:00 [pubmed]
PHST- 2009/12/16 06:00 [medline]
AID - PAI819 [pii]
AID - 10.1111/j.1399-3038.2008.00819.x [doi]
PST - ppublish
SO  - Pediatr Allergy Immunol. 2009 Sep;20(6):563-70. doi: 
      10.1111/j.1399-3038.2008.00819.x. Epub 2009 May 31.