PMID- 19497597
OWN - NLM
STAT- MEDLINE
DCOM- 20090811
LR  - 20220410
IS  - 1532-8600 (Electronic)
IS  - 0026-0495 (Linking)
VI  - 58
IP  - 8
DP  - 2009 Aug
TI  - Effect of resistance exercise, with or without carbohydrate supplementation, on 
      plasma ghrelin concentrations and postexercise hunger and food intake.
PG  - 1191-9
LID - 10.1016/j.metabol.2009.03.018 [doi]
AB  - The effects of resistance exercise with and without carbohydrate (CHO) 
      supplementation on hunger, postexercise food intake, and plasma ghrelin, an 
      orexigenic gastric peptide, are poorly characterized. We examined the individual 
      and combined effects of a resistance exercise bout and CHO consumption on plasma 
      ghrelin and postexercise food intake. Twenty-one apparently healthy young male 
      participants ([mean +/- SD] age = 20 +/- 1.8 years, body mass index = 24.8 +/- 
      3.3 kg/m(2)) completed in random order 3 treatment conditions: (1) 
      ExCHO-80-minute resistance exercise bout while consuming CHO ( approximately 77 g 
      CHO, 306 kcal); (2) ExPLA-identical exercise with a non=caloric placebo; and (3) 
      NoExCHO-no-exercise trial of quiet sitting and CHO consumption. Blood samples 
      were obtained before, during, and immediately postexercise, and 110 minutes after 
      exercise. At 2 hours postexercise, they were provided a buffet of food from which 
      they ate ad libitum. There was a significant time x treatment interaction for 
      plasma ghrelin caused by a decline from pre- to postexercise in the 2 exercise 
      conditions compared with an increase over time in the NoExCHO condition. At 110 
      minutes postexercise, ghrelin was 21% and 13% lower in ExCHO and ExPLA compared 
      with NoExCHO (both Ps < .05). However, despite the lower ghrelin concentrations 
      for the 2 exercise conditions, the subjective ratings of hunger were not lower 
      for these conditions compared with the NoExCHO. There were no differences in 
      absolute ad libitum energy intake from the buffet among the 3 conditions, but 
      relative energy intake from the buffet accounting for the estimated cost of 
      exercise was lowest among the 2 exercise conditions. We conclude that (1) weight 
      lifting lowers plasma ghrelin concentrations during exercise and attenuates its 
      rise during the postexercise period in young men and (2) the lower plasma ghrelin 
      concentration is not associated with lower subjective feelings of hunger measured 
      100 minutes postexercise, but is associated with a lower relative food intake.
FAU - Ballard, Tasha P
AU  - Ballard TP
AD  - Department of Food Science and Human Nutrition, Colorado State University, Fort 
      Collins, CO 80523, USA.
FAU - Melby, Christopher L
AU  - Melby CL
FAU - Camus, Heidi
AU  - Camus H
FAU - Cianciulli, Matthew
AU  - Cianciulli M
FAU - Pitts, Julie
AU  - Pitts J
FAU - Schmidt, Stacy
AU  - Schmidt S
FAU - Hickey, Matthew S
AU  - Hickey MS
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
DEP - 20090618
PL  - United States
TA  - Metabolism
JT  - Metabolism: clinical and experimental
JID - 0375267
RN  - 0 (Blood Glucose)
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Ghrelin)
RN  - 0 (Insulin)
SB  - IM
MH  - Adolescent
MH  - Basal Metabolism
MH  - Blood Glucose/metabolism
MH  - Dietary Carbohydrates/*administration & dosage
MH  - *Dietary Supplements
MH  - Double-Blind Method
MH  - Eating
MH  - *Energy Intake
MH  - Exercise
MH  - Ghrelin/*blood
MH  - Humans
MH  - *Hunger
MH  - Insulin/blood
MH  - Male
MH  - Research Design
MH  - *Resistance Training
MH  - Satiation
MH  - Young Adult
EDAT- 2009/06/06 09:00
MHDA- 2009/08/12 09:00
CRDT- 2009/06/06 09:00
PHST- 2008/09/04 00:00 [received]
PHST- 2009/03/23 00:00 [accepted]
PHST- 2009/06/06 09:00 [entrez]
PHST- 2009/06/06 09:00 [pubmed]
PHST- 2009/08/12 09:00 [medline]
AID - S0026-0495(09)00128-0 [pii]
AID - 10.1016/j.metabol.2009.03.018 [doi]
PST - ppublish
SO  - Metabolism. 2009 Aug;58(8):1191-9. doi: 10.1016/j.metabol.2009.03.018. Epub 2009 
      Jun 18.