PMID- 19501793
OWN - NLM
STAT- MEDLINE
DCOM- 20090727
LR  - 20220330
IS  - 1879-0070 (Electronic)
IS  - 0732-8893 (Linking)
VI  - 64
IP  - 3
DP  - 2009 Jul
TI  - Immune reconstitution inflammatory syndrome after cessation of the tumor necrosis 
      factor alpha blocker adalimumab in cryptococcal pneumonia.
PG  - 327-30
LID - 10.1016/j.diagmicrobio.2009.03.019 [doi]
AB  - Tumor necrosis factor alpha antagonists have proven efficacious for a variety of 
      autoimmune-mediated diseases. However, recent data have highlighted the risk of 
      invasive fungal infections with their use. These agents are typically 
      discontinued when infectious complications occur during therapy; however, the 
      immune reconstitution inflammatory syndrome (IRIS) may be seen after drug 
      cessation. We describe the 1st case of IRIS secondary to cryptococcal pneumonia 
      after cessation of adalimumab.
FAU - Cadena, Jose
AU  - Cadena J
AD  - Department of Medicine, University of Texas Health Science Center at San Antonio, 
      78229, USA.
FAU - Thompson, George R 3rd
AU  - Thompson GR 3rd
FAU - Ho, Tony T
AU  - Ho TT
FAU - Medina, Edward
AU  - Medina E
FAU - Hughes, Darrel W
AU  - Hughes DW
FAU - Patterson, Thomas F
AU  - Patterson TF
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Diagn Microbiol Infect Dis
JT  - Diagnostic microbiology and infectious disease
JID - 8305899
RN  - 0 (Antibodies, Monoclonal)
RN  - 0 (Antibodies, Monoclonal, Humanized)
RN  - 0 (Immunologic Factors)
RN  - FYS6T7F842 (Adalimumab)
SB  - IM
MH  - Adalimumab
MH  - Antibodies, Monoclonal/*therapeutic use
MH  - Antibodies, Monoclonal, Humanized
MH  - Cryptococcosis/*complications/drug therapy
MH  - Female
MH  - Humans
MH  - *Immune Reconstitution Inflammatory Syndrome
MH  - Immunologic Factors/*therapeutic use
MH  - Middle Aged
MH  - Pneumonia/*complications/drug therapy
MH  - Withholding Treatment
EDAT- 2009/06/09 09:00
MHDA- 2009/07/28 09:00
CRDT- 2009/06/09 09:00
PHST- 2009/02/09 00:00 [received]
PHST- 2009/03/16 00:00 [revised]
PHST- 2009/03/17 00:00 [accepted]
PHST- 2009/06/09 09:00 [entrez]
PHST- 2009/06/09 09:00 [pubmed]
PHST- 2009/07/28 09:00 [medline]
AID - S0732-8893(09)00108-4 [pii]
AID - 10.1016/j.diagmicrobio.2009.03.019 [doi]
PST - ppublish
SO  - Diagn Microbiol Infect Dis. 2009 Jul;64(3):327-30. doi: 
      10.1016/j.diagmicrobio.2009.03.019.