PMID- 19505773
OWN - NLM
STAT- MEDLINE
DCOM- 20090929
LR  - 20211020
IS  - 1879-0046 (Electronic)
IS  - 0376-8716 (Print)
IS  - 0376-8716 (Linking)
VI  - 104
IP  - 1-2
DP  - 2009 Sep 1
TI  - Association of major depression with subtypes of nicotine dependence found among 
      adult daily smokers: a latent class analysis.
PG  - 126-32
LID - 10.1016/j.drugalcdep.2009.04.013 [doi]
AB  - Nicotine dependence (ND) and major depression (MD) are highly prevalent disorders 
      that frequently co-occur. Less is known about which aspects of ND are most 
      strongly associated with MD. The present study was designed to determine if 
      subtypes of smokers exist and differ in their risk of MD and lifetime MD 
      symptoms. Latent class analysis was used to identify profiles of DSM-IV ND 
      criteria for 8,842 daily smokers drawn from the larger 2001-2002 National 
      Epidemiologic Survey on Alcohol and Related Conditions (NESARC). We found 
      evidence for 4 distinct subtypes of smokers mainly characterized by increasing 
      levels of ND severity, by number of criteria endorsed. We found a dose-response 
      relationship between classes by increasing ND severity and odds of past-year MD 
      and lifetime depression criteria. Class 2 was characterized by higher symptom 
      endorsement probabilities (SEPs) for wider range of ND criteria and a higher odds 
      of MD (OR=3.66) compared to class 3, which was characterized by higher SEPs for 
      physiological ND criteria, higher prevalence of ND (class 2, 71.50% vs. class 3, 
      81.57%), and a lower odds of MD (OR=2.15). A post hoc contrast showed these two 
      distinct classes of respondents with mild to moderate ND significantly differed 
      in their likelihood of MD comorbidity (F=12.25, 1 df, p=0.0008). ND severity 
      mainly characterized the classes, but unique differences may exist between 
      smokers with mild to moderate ND. Individuals with symptom profiles not 
      characterized by physiological dependence endorse wider range of ND criteria and 
      have a higher likelihood of MD.
FAU - Manley, Melinda J
AU  - Manley MJ
AD  - Department of Epidemiology & Public Health, Yale University School of Medicine, 
      60 College Street, New Haven, CT 06520, USA. m.j.manley@med.umcg.nl
FAU - de Jonge, Peter
AU  - de Jonge P
FAU - Kershaw, Trace S
AU  - Kershaw TS
FAU - Desai, Rani A
AU  - Desai RA
FAU - Lin, Haiqun
AU  - Lin H
FAU - Kasl, Stanislav V
AU  - Kasl SV
LA  - eng
GR  - T32 MH014235/MH/NIMH NIH HHS/United States
GR  - T32-MH14235/MH/NIMH NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
DEP - 20090607
PL  - Ireland
TA  - Drug Alcohol Depend
JT  - Drug and alcohol dependence
JID - 7513587
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Affect
MH  - Data Interpretation, Statistical
MH  - Depressive Disorder, Major/*complications/*psychology
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Models, Statistical
MH  - Multivariate Analysis
MH  - Population
MH  - Psychiatric Status Rating Scales
MH  - Reproducibility of Results
MH  - Socioeconomic Factors
MH  - Tobacco Use Disorder/*complications/*psychology
MH  - Young Adult
PMC - PMC3881368
MID - NIHMS526902
COIS- Conflicts of interest All authors declare that they have no conflicts of 
      interest.
EDAT- 2009/06/10 09:00
MHDA- 2009/09/30 06:00
PMCR- 2014/01/06
CRDT- 2009/06/10 09:00
PHST- 2008/08/14 00:00 [received]
PHST- 2009/04/14 00:00 [revised]
PHST- 2009/04/21 00:00 [accepted]
PHST- 2009/06/10 09:00 [entrez]
PHST- 2009/06/10 09:00 [pubmed]
PHST- 2009/09/30 06:00 [medline]
PHST- 2014/01/06 00:00 [pmc-release]
AID - S0376-8716(09)00154-9 [pii]
AID - 10.1016/j.drugalcdep.2009.04.013 [doi]
PST - ppublish
SO  - Drug Alcohol Depend. 2009 Sep 1;104(1-2):126-32. doi: 
      10.1016/j.drugalcdep.2009.04.013. Epub 2009 Jun 7.