PMID- 19508352 OWN - NLM STAT- MEDLINE DCOM- 20101210 LR - 20220309 IS - 1463-1326 (Electronic) IS - 1462-8902 (Linking) VI - 11 IP - 8 DP - 2009 Aug TI - Obstructive sleep apnoea in patients with type 2 diabetes: aetiology and implications for clinical care. PG - 733-41 LID - 10.1111/j.1463-1326.2009.01045.x [doi] AB - Recent attention has been drawn to the close association between obstructive sleep apnoea (OSA) and type 2 diabetes mellitus (T2DM). Debate has included much discussion about cause and effect with mechanisms proposed whereby one condition might cause the other. However, both clearly share a common phenotype, namely, obesity that overlaps considerably with the other components of the metabolic syndrome, hypertension and hyperlipidaemia. It would therefore appear likely that all are manifestations of the same basic pathological processes. Possible interacting aetiological mechanisms are reviewed along with treatment options. A recent report by the International Diabetes Federation has made recommendations to raise awareness of possible OSA in patients with T2DM and also for screening for hypertension, hyperlipidaemia and T2DM in patients with known OSA. The clinical implications are discussed. FAU - Idris, Iskandar AU - Idris I AD - Department of Diabetes and Endocrinology, Sherwood Forest Hospitals Foundation Trust, Nottinghamshire, UK. iidris@aol.com FAU - Hall, Andrew P AU - Hall AP FAU - O'Reilly, John AU - O'Reilly J FAU - Barnett, Anthony AU - Barnett A FAU - Allen, Martin AU - Allen M FAU - Andrews, Robert AU - Andrews R FAU - Grunstein, Phillipe AU - Grunstein P FAU - Lewis, Keir AU - Lewis K FAU - Goenka, Niru AU - Goenka N FAU - Wilding, John P AU - Wilding JP LA - eng PT - Journal Article PT - Review DEP - 20090607 PL - England TA - Diabetes Obes Metab JT - Diabetes, obesity & metabolism JID - 100883645 SB - IM MH - Cardiovascular Diseases/complications MH - Continuous Positive Airway Pressure MH - Diabetes Mellitus, Type 2/*complications MH - Female MH - Humans MH - Hyperlipidemias/complications MH - Hypertension/complications MH - Male MH - Metabolic Syndrome/complications MH - Obesity/complications MH - Risk MH - Sleep Apnea, Obstructive/*complications/diagnosis/therapy EDAT- 2009/06/11 09:00 MHDA- 2010/12/14 06:00 CRDT- 2009/06/11 09:00 PHST- 2009/06/11 09:00 [entrez] PHST- 2009/06/11 09:00 [pubmed] PHST- 2010/12/14 06:00 [medline] AID - DOM1045 [pii] AID - 10.1111/j.1463-1326.2009.01045.x [doi] PST - ppublish SO - Diabetes Obes Metab. 2009 Aug;11(8):733-41. doi: 10.1111/j.1463-1326.2009.01045.x. Epub 2009 Jun 7.