PMID- 19516783
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20130704
LR  - 20190516
IS  - 1094-4087 (Electronic)
IS  - 1094-4087 (Linking)
VI  - 14
IP  - 13
DP  - 2006 Jun 26
TI  - Clutter rejection filters for optical Doppler tomography.
PG  - 6103-12
AB  - The phase-resolved (PR) method is widely used in optical Doppler tomography (ODT) 
      to estimate flow velocity from sequential axial line (A-line) signals. However, 
      the A-line signal contains clutter components induced by stationary or relative 
      slow moving clutter scatterers such as the blood vessel wall or the overall 
      sample with motion artifacts. The clutter component affects the accuracy in 
      quantifying Doppler flow. In this paper, we present a delay line filter (DLF) to 
      reject the clutter effect and enables moving-scatterer-sensitive ODT (MSS-ODT) 
      imaging of flow. The frequency response of DLFs of different orders is 
      theoretically analyzed and we find that a first-order phase-shifted DLF is 
      effective for clutter rejection and for improving the sensitivity to moving 
      scatterers such as moving blood cells. The proposed MSS-ODT method has been 
      experimentally applied to Doppler flow imaging in a capillary flow phantom and a 
      mouse ear in vivo. The ODT data were acquired using a real-time spectral-domain 
      optical coherence tomography (SD-OCT) system with an A-line acquisition rate of 
      12.3k/s. Doppler flow images obtained with MSS-ODT and the conventional PR-ODT 
      techniques are compared and MSS-ODT is found to be more sensitive to Doppler flow 
      and more accurate in determining vessel size. Small blood vessels that might be 
      masked by clutter signals in PR-OCT are successfully recovered by MSS-ODT.
FAU - Ren, Hongwu
AU  - Ren H
FAU - Li, Xingde
AU  - Li X
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Opt Express
JT  - Optics express
JID - 101137103
EDAT- 2006/06/26 00:00
MHDA- 2006/06/26 00:01
CRDT- 2009/06/12 09:00
PHST- 2009/06/12 09:00 [entrez]
PHST- 2006/06/26 00:00 [pubmed]
PHST- 2006/06/26 00:01 [medline]
AID - 90566 [pii]
AID - 10.1364/oe.14.006103 [doi]
PST - ppublish
SO  - Opt Express. 2006 Jun 26;14(13):6103-12. doi: 10.1364/oe.14.006103.