PMID- 19516855 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20121002 LR - 20190516 IS - 1094-4087 (Electronic) IS - 1094-4087 (Linking) VI - 14 IP - 15 DP - 2006 Jul 24 TI - Pulsed illumination spectral-domain optical coherence tomography for human retinal imaging. PG - 6739-48 AB - We present pulsed illumination spectral-domain optical coherence tomography (SD-OCT) for in vivo human retinal imaging. We analyze the signal-to-noise (SNR) for continuous wave (CW) and pulsed illumination SD-OCT. The lateral beam scan motion is responsible for a SNR drop due to lateral scanning induced interference fringe washout. Pulsed illumination can reduce the SNR drop by shorter sample illumination time during the integration time of a camera. First, we demonstrate the SNR benefit of pulsed illumination over CW as function of lateral scan speed for a paper sample. Finally, we show better SNR in retinal images of a normal subject with pulsed illumination SD-OCT over CW at high lateral scanning speed. FAU - You, Jang-Woo AU - You JW FAU - Chen, Teresa C AU - Chen TC FAU - Mujat, Mircea AU - Mujat M FAU - Park, B Hyle AU - Park BH FAU - de Boer, Johannes F AU - de Boer JF LA - eng PT - Journal Article PL - United States TA - Opt Express JT - Optics express JID - 101137103 EDAT- 2006/07/24 00:00 MHDA- 2006/07/24 00:01 CRDT- 2009/06/12 09:00 PHST- 2009/06/12 09:00 [entrez] PHST- 2006/07/24 00:00 [pubmed] PHST- 2006/07/24 00:01 [medline] AID - 92242 [pii] AID - 10.1364/oe.14.006739 [doi] PST - ppublish SO - Opt Express. 2006 Jul 24;14(15):6739-48. doi: 10.1364/oe.14.006739.