PMID- 19520153 OWN - NLM STAT- MEDLINE DCOM- 20091207 LR - 20101118 IS - 1089-8646 (Electronic) IS - 0888-7543 (Linking) VI - 94 IP - 3 DP - 2009 Sep TI - An extended anchored linkage map and virtual mapping for the American mink genome based on homology to human and dog. PG - 204-10 LID - 10.1016/j.ygeno.2009.05.014 [doi] AB - In this report we present an extended linkage map of the American mink (Neovison vison) consisting of 157 microsatellite markers and comprising at least one linkage group for each of the autosomes. Each linkage group has been assigned to a chromosome and oriented by fluorescence in situ hybridization (FISH) and/or by means of human/dog/mink comparative homology. The average interval between markers is 8.5 cM and the linkage groups collectively span 1340 cM. In addition, 217 and 275 mink microsatellites have been placed on human and dog genomes, respectively. In conjunction with the existing comparative human/dog/mink data, these assignments represent useful virtual maps for the American mink genome. Comparison of the current human/dog assembled sequential map with the existing Zoo-FISH-based human/dog/mink maps helped to refine the human/dog/mink comparative map. Furthermore, comparison of the human and dog genome assemblies revealed a number of large synteny blocks, some of which are corroborated by data from the mink linkage map. FAU - Anistoroaei, R AU - Anistoroaei R AD - University of Copenhagen, Department of Basic Animal and Veterinary Sciences, Frederiksberg C, Denmark. ran@life.ku.dk FAU - Ansari, S AU - Ansari S FAU - Farid, A AU - Farid A FAU - Benkel, B AU - Benkel B FAU - Karlskov-Mortensen, P AU - Karlskov-Mortensen P FAU - Christensen, K AU - Christensen K LA - eng PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20090609 PL - United States TA - Genomics JT - Genomics JID - 8800135 SB - IM MH - Animals MH - Base Sequence MH - *Chromosome Mapping MH - Chromosomes, Artificial, Bacterial MH - Dogs MH - Genetic Linkage/*genetics MH - Genome MH - Humans MH - In Situ Hybridization, Fluorescence MH - Microsatellite Repeats/genetics MH - Mink/*genetics MH - Molecular Sequence Data EDAT- 2009/06/13 09:00 MHDA- 2009/12/16 06:00 CRDT- 2009/06/13 09:00 PHST- 2009/01/28 00:00 [received] PHST- 2009/05/20 00:00 [revised] PHST- 2009/05/28 00:00 [accepted] PHST- 2009/06/13 09:00 [entrez] PHST- 2009/06/13 09:00 [pubmed] PHST- 2009/12/16 06:00 [medline] AID - S0888-7543(09)00127-X [pii] AID - 10.1016/j.ygeno.2009.05.014 [doi] PST - ppublish SO - Genomics. 2009 Sep;94(3):204-10. doi: 10.1016/j.ygeno.2009.05.014. Epub 2009 Jun 9.