PMID- 19521019 OWN - NLM STAT- MEDLINE DCOM- 20091215 LR - 20220311 IS - 1347-4820 (Electronic) IS - 1346-9843 (Linking) VI - 73 IP - 8 DP - 2009 Aug TI - Incidence and clinical predictors of deep vein thrombosis in patients hospitalized with heart failure in Japan. PG - 1513-7 AB - BACKGROUND: The aim of this study was to clarify the incidence and clinical predictors of deep vein thrombosis (DVT) in patients with congestive heart failure (CHF) in Japan. METHODS AND RESULTS: Between January 2003 and January 2008, 161 patients were admitted to Mie University Hospital with a diagnosis of CHF and underwent venous compression ultrasonography. Of them, 18 patients (11.2%) were diagnosed with DVT. As defined by New York Heart Association (NYHA) functional class, class IV patients had a higher incidence rate of DVT than those in class II or III (class II: 3 patients (4.4%), class III: 2 patients (4.8%), class IV: 13 patients (25.5%), P<0.01). Multiple logistic regression analysis identified that NYHA functional class and poor collapsibility of the inferior vena cava on ultrasonography as independent predictors of DVT (odds ratios (OR) 3.74, 95% confidence interval (CI) 1.72-8.16, P<0.01 and OR 4.43, 95%CI 1.36-14.43, P<0.05, respectively). Therapy without anticoagulation also indicated a significant increase in DVT incidence in CHF patients (OR 3.71, 95%CI 1.13-12.18, P<0.05). CONCLUSIONS: Patients with CHF have a high risk for DVT and the risk increases according to NYHA functional class, poor IVC collapsibility or therapy without anticoagulation. FAU - Ota, Satoshi AU - Ota S AD - Department of Cardiology, Mie University Graduate School of Medicine, Tsu, Japan. FAU - Yamada, Norikazu AU - Yamada N FAU - Tsuji, Akihiro AU - Tsuji A FAU - Ishikura, Ken AU - Ishikura K FAU - Nakamura, Mashio AU - Nakamura M FAU - Ito, Masaaki AU - Ito M LA - eng PT - Journal Article DEP - 20090612 PL - Japan TA - Circ J JT - Circulation journal : official journal of the Japanese Circulation Society JID - 101137683 SB - IM MH - Female MH - Heart Failure/*complications/epidemiology MH - Heart Function Tests MH - Hospitalization MH - Humans MH - Incidence MH - Japan MH - Logistic Models MH - Male MH - Predictive Value of Tests MH - Prospective Studies MH - Risk Factors MH - Ultrasonography MH - Vena Cava, Inferior/diagnostic imaging MH - Venous Thrombosis/diagnostic imaging/*epidemiology/*etiology EDAT- 2009/06/13 09:00 MHDA- 2009/12/16 06:00 CRDT- 2009/06/13 09:00 PHST- 2009/06/13 09:00 [entrez] PHST- 2009/06/13 09:00 [pubmed] PHST- 2009/12/16 06:00 [medline] AID - JST.JSTAGE/circj/CJ-08-0990 [pii] AID - 10.1253/circj.cj-08-0990 [doi] PST - ppublish SO - Circ J. 2009 Aug;73(8):1513-7. doi: 10.1253/circj.cj-08-0990. Epub 2009 Jun 12.