PMID- 19525905
OWN - NLM
STAT- MEDLINE
DCOM- 20090831
LR  - 20191111
IS  - 0966-0461 (Print)
IS  - 0966-0461 (Linking)
VI  - 18
IP  - 11
DP  - 2009 Jun 11-24
TI  - The use of MelMax in the healing of chronic wounds.
PG  - S30, S32, S34-5
AB  - Chronic wounds can have detrimental consequences for the quality of life of 
      patients as well as presenting a huge financial burden to the NHS. An imbalance 
      in the level of matrix metalloproteinases (MMPs) and the tissue inhibitors of 
      MMPs (TIMPs) in chronic wounds impedes the healing process. In addition, high 
      levels of bacteria in the wound bed are a common feature of chronic wounds and 
      also cited as a major cause of delayed healing. The aim of this article is to 
      look in more detail at the role of MMPs in wound healing as well as the 
      antimicrobial properties of honey when combined with a dressing to combat wound 
      infection. The article also introduces a new dressing, MelMax (distributed by 
      CliniMed), which utilizes protease regulation and the antimicrobial properties of 
      honey when addressing chronic wound infection. Short-term case studies are used 
      to demonstrate how the dressing was successfully incorporated into the author's 
      practice.
FAU - Lloyd Jones, Menna
AU  - Lloyd Jones M
AD  - Tissue Viability, North West Wales NHS Trust.
LA  - eng
PT  - Journal Article
PL  - England
TA  - Br J Nurs
JT  - British journal of nursing (Mark Allen Publishing)
JID - 9212059
RN  - EC 3.4.24.- (Matrix Metalloproteinases)
MH  - Bandages
MH  - Chronic Disease
MH  - Honey
MH  - Humans
MH  - Matrix Metalloproteinases/physiology
MH  - State Medicine
MH  - United Kingdom
MH  - *Wound Healing
MH  - Wounds and Injuries/*therapy
EDAT- 2009/06/16 09:00
MHDA- 2009/09/01 06:00
CRDT- 2009/06/16 09:00
PHST- 2009/06/16 09:00 [entrez]
PHST- 2009/06/16 09:00 [pubmed]
PHST- 2009/09/01 06:00 [medline]
AID - 10.12968/bjon.2009.18.sup4.42730 [doi]
PST - ppublish
SO  - Br J Nurs. 2009 Jun 11-24;18(11):S30, S32, S34-5. doi: 
      10.12968/bjon.2009.18.sup4.42730.