PMID- 19526340 OWN - NLM STAT- MEDLINE DCOM- 20091104 LR - 20211020 IS - 1573-6709 (Electronic) IS - 0033-2720 (Linking) VI - 80 IP - 3 DP - 2009 Sep TI - Insight, global functioning and psychopathology amongst in-patient clients with schizophrenia. PG - 155-65 LID - 10.1007/s11126-009-9103-9 [doi] AB - To explore whether cognitive impairment and global functioning can predict the degree of insight into illness as well as whether insight is mediated by specific symptom dimensions of psychopathology in schizophrenia. A dimensional/cross sectional approach was used. A mixed group of clients (n = 36) were assessed as part of a routine clinical evaluation. The Wechsler Adult Intelligence Scale (WAIS) was used as a measure of intellectual performance, the Brief Symptom Inventory (BSI) was used as a measure of general psychopathology while the Global Assessment of Functioning (GAF) scale assessed clients' psychosocial functioning; insight was assessed with the Insight and Treatment Attitudes Questionnaire (ITAQ). The correlation matrix of all outcome variables was examined; confounding effects of illness duration were tested by partial correlation analyses. GAF correlated with insight (rho = 0.41, P = 0.01) and the interpersonal sensitivity dimension of BSI (rho = -0.38, P = 0.03. Insight correlated positively with the anxiety (rho = 0.38, P = 0.03) and psychoticism (rho = 0.36, P = 0.04) dimensions of BSI. Our results suggest that insight is part of the phenomenology in schizophrenia, not being determined by neurocognitive disturbances. Improved insight was associated with more frequent psychotic symptoms endorsement, higher levels of anxiety and less severe psychopathological symptoms and difficulties in psychosocial functioning; clients with more pronounced difficulties in their personal and social interactions exhibited worse psychosocial functioning and more severe psychopathological symptoms. FAU - Stefanopoulou, Evgenia AU - Stefanopoulou E AD - University of East Anglia, Norwich, UK. FAU - Lafuente, Antonio Romero AU - Lafuente AR FAU - Saez Fonseca, J Andres AU - Saez Fonseca JA FAU - Huxley, Adam AU - Huxley A LA - eng PT - Journal Article DEP - 20090613 PL - United States TA - Psychiatr Q JT - The Psychiatric quarterly JID - 0376465 SB - IM MH - Adult MH - *Attitude to Health MH - *Cognition MH - Cohort Studies MH - Female MH - Humans MH - Interpersonal Relations MH - Male MH - Middle Aged MH - Psychiatric Status Rating Scales MH - Quality of Life MH - Schizophrenia/*diagnosis MH - *Schizophrenic Psychology MH - Severity of Illness Index MH - Social Behavior EDAT- 2009/06/16 09:00 MHDA- 2009/11/05 06:00 CRDT- 2009/06/16 09:00 PHST- 2009/02/25 00:00 [received] PHST- 2009/04/14 00:00 [accepted] PHST- 2009/06/16 09:00 [entrez] PHST- 2009/06/16 09:00 [pubmed] PHST- 2009/11/05 06:00 [medline] AID - 10.1007/s11126-009-9103-9 [doi] PST - ppublish SO - Psychiatr Q. 2009 Sep;80(3):155-65. doi: 10.1007/s11126-009-9103-9. Epub 2009 Jun 13.