PMID- 19532973 OWN - NLM STAT- MEDLINE DCOM- 20090811 LR - 20090617 IS - 1473-0197 (Print) IS - 1473-0189 (Linking) VI - 9 IP - 13 DP - 2009 Jul 7 TI - Tuneable hydrophoretic separation using elastic deformation of poly(dimethylsiloxane). PG - 1962-5 LID - 10.1039/b820364d [doi] AB - This paper demonstrates a method for tuning elastomeric microchannels for hydrophoretic separation made in poly(dimethylsiloxane) (PDMS). Uniform compressive strain is imposed on the elastomeric microchannel between two acrylic substrates by fastening the bolts. The elastomeric microchannel can change its cross-section during compression, simultaneously tuning the criterion for hydrophoretic ordering. The change of the channel cross-section under compression is studied using a confocal microscope and finite element method (FEM). By pressing the channel for hydrophoretic separation, we achieved tuning of the separation criterion from 7 to 2.5 microm in particle diameter. FAU - Choi, Sungyoung AU - Choi S AD - Department of Bio and Brain Engineering, College of Life Science and Bioengineering, KAIST, 335 Gwahangno, Yuseong-gu, Daejeon, 305-701, Republic of Korea. FAU - Park, Je-Kyun AU - Park JK LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20090313 PL - England TA - Lab Chip JT - Lab on a chip JID - 101128948 RN - 0 (Dimethylpolysiloxanes) SB - IM MH - Dimethylpolysiloxanes/*chemistry MH - Elasticity MH - Equipment Design MH - Filtration/instrumentation/*methods MH - Microfluidic Analytical Techniques/*instrumentation/*methods MH - Particle Size MH - Stress, Mechanical MH - Surface Properties EDAT- 2009/06/18 09:00 MHDA- 2009/08/12 09:00 CRDT- 2009/06/18 09:00 PHST- 2009/06/18 09:00 [entrez] PHST- 2009/06/18 09:00 [pubmed] PHST- 2009/08/12 09:00 [medline] AID - 10.1039/b820364d [doi] PST - ppublish SO - Lab Chip. 2009 Jul 7;9(13):1962-5. doi: 10.1039/b820364d. Epub 2009 Mar 13.