PMID- 195354
OWN - NLM
STAT- MEDLINE
DCOM- 19770902
LR  - 20191028
IS  - 0098-0366 (Print)
IS  - 0098-0366 (Linking)
VI  - 2
IP  - 3
DP  - 1976 May
TI  - Genetic homology between man and the chimpanzee: syntenic relationships of genes 
      for galactokinase and thymidine kinase and adenovirus-12-induced gaps using 
      chimpanzee-mouse somatic cell hybrids.
PG  - 205-13
AB  - The induction by adenovirus-12 of a site-specific gap and assignment of the 
      chimpanzee genes for thymidine kinase and galactokinase were studied by utilizing 
      chimpanzee-mouse hybrid cells. It has been shown that adenovirus-12 induces a 
      specific gap in the long arm of human chromosome 17 (HS 17); with 
      chimpanzee-mouse hybrid cells the specific gap appears on the short arm of the 
      chimpanzee homolog [PTR 19 (HS 17)] of HS 17. This result supports the proposed 
      relationship of HS 17 to PTR 19 (HS 17) by means of a pericentric inversion. The 
      chimpanzee thymidine kinase and galactokinase genes were assigned to PTR 19 (HS 
      17), further confirming the homology to HS 17. Other syntenic relationships and 
      gene assignments were consistent with proposed homologies between chimpanzee and 
      human chromosomes.
FAU - Chen, S
AU  - Chen S
FAU - McDougall, J K
AU  - McDougall JK
FAU - Creagan, R P
AU  - Creagan RP
FAU - Lewis, V
AU  - Lewis V
FAU - Ruddle, F H
AU  - Ruddle FH
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Somatic Cell Genet
JT  - Somatic cell genetics
JID - 7506054
RN  - EC 2.7.- (Phosphotransferases)
RN  - EC 2.7.1.21 (Thymidine Kinase)
SB  - IM
MH  - Adenoviridae
MH  - Animals
MH  - Chromosome Aberrations
MH  - Chromosome Mapping
MH  - Chromosomes
MH  - *Genes
MH  - Humans
MH  - Hybrid Cells
MH  - Mice
MH  - *Pan troglodytes
MH  - Phosphotransferases/*biosynthesis
MH  - Species Specificity
MH  - Thymidine Kinase/*biosynthesis
EDAT- 1976/05/01 00:00
MHDA- 1976/05/01 00:01
CRDT- 1976/05/01 00:00
PHST- 1976/05/01 00:00 [pubmed]
PHST- 1976/05/01 00:01 [medline]
PHST- 1976/05/01 00:00 [entrez]
AID - 10.1007/BF01538959 [doi]
PST - ppublish
SO  - Somatic Cell Genet. 1976 May;2(3):205-13. doi: 10.1007/BF01538959.