PMID- 19545814 OWN - NLM STAT- MEDLINE DCOM- 20090904 LR - 20220318 IS - 1873-4502 (Electronic) IS - 0886-3350 (Linking) VI - 35 IP - 7 DP - 2009 Jul TI - Comparison of the incidence and visual significance of posterior capsule opacification between multifocal spherical, monofocal spherical, and monofocal aspheric intraocular lenses. PG - 1234-8 LID - 10.1016/j.jcrs.2009.03.013 [doi] AB - PURPOSE: To determine and compare the incidence of posterior capsule opacification (PCO) and neodymium:YAG (Nd:YAG) laser capsulotomy after implantation of 3 intraocular lens types (IOLs). SETTING: Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA. METHODS: This retrospective chart review comprised eyes having uneventful phacoemulsification and implantation of 1 of 3 AcrySof IOLs: ReSTOR SN60D3 (multifocal spherical group), Natural SN60AT (monofocal spherical group), or IQ SN60WF (monofocal aspheric group). Eyes were matched by age, sex, and follow-up. The PCO rate, Nd:YAG capsulotomy rate, time from surgery to PCO diagnosis, and time from surgery to Nd:YAG capsulotomy were assessed. RESULTS: Charts of 225 eyes (75 in each group) with a mean follow-up of 15.9 months +/- 6.5 (SD) were evaluated. The PCO rate was 42.7% in the multifocal spherical group, 28.0% in the monofocal spherical group, and 14.7% in the monofocal aspheric group. The Nd:YAG capsulotomy rate was 25.3%, 17.3%, and 4.0%, respectively. The difference in the Nd:YAG rate was statistically significantly higher in the multifocal and monofocal spherical groups than in the monofocal aspheric group (P<.001 and P<.008, respectively) but was not significantly different between the 2 spherical IOL groups (P = .232). The time from surgery to PCO documentation was not significantly different between the 3 groups. CONCLUSIONS: Intraocular lens configuration may have contributed to the difference in the PCO rate between the 2 spherical IOLs and the aspheric IOL. Based on the Nd:YAG rate as an indicator for visual significance, PCO may be less visually significant in eyes with the aspheric IOL than in eyes with 1 of the spherical IOLs. FAU - Biber, Joseph M AU - Biber JM AD - Magill Research Center for Vision Correction, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina 29425, USA. FAU - Sandoval, Helga P AU - Sandoval HP FAU - Trivedi, Rupal H AU - Trivedi RH FAU - de Castro, Luis E Fernandez AU - de Castro LE FAU - French, John W AU - French JW FAU - Solomon, Kerry D AU - Solomon KD LA - eng GR - EY14793/EY/NEI NIH HHS/United States PT - Comparative Study PT - Journal Article PT - Research Support, N.I.H., Extramural PT - Research Support, Non-U.S. Gov't PL - United States TA - J Cataract Refract Surg JT - Journal of cataract and refractive surgery JID - 8604171 SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - Cataract/*etiology/therapy MH - Female MH - Follow-Up Studies MH - Humans MH - Incidence MH - Laser Therapy MH - Lasers, Solid-State/therapeutic use MH - Lens Capsule, Crystalline/*pathology/surgery MH - Lens Implantation, Intraocular MH - *Lenses, Intraocular MH - Male MH - Middle Aged MH - *Phacoemulsification MH - *Postoperative Complications MH - Pseudophakia/physiopathology MH - Retrospective Studies MH - Visual Acuity/*physiology EDAT- 2009/06/24 09:00 MHDA- 2009/09/05 06:00 CRDT- 2009/06/24 09:00 PHST- 2008/12/19 00:00 [received] PHST- 2009/02/28 00:00 [revised] PHST- 2009/03/02 00:00 [accepted] PHST- 2009/06/24 09:00 [entrez] PHST- 2009/06/24 09:00 [pubmed] PHST- 2009/09/05 06:00 [medline] AID - S0886-3350(09)00340-X [pii] AID - 10.1016/j.jcrs.2009.03.013 [doi] PST - ppublish SO - J Cataract Refract Surg. 2009 Jul;35(7):1234-8. doi: 10.1016/j.jcrs.2009.03.013.