PMID- 19546284
OWN - NLM
STAT- MEDLINE
DCOM- 20091117
LR  - 20181201
IS  - 1472-0213 (Electronic)
IS  - 1472-0205 (Linking)
VI  - 26
IP  - 7
DP  - 2009 Jul
TI  - Early administration of thrombolysis can prevent myocardial necrosis: time is 
      myocardium.
PG  - 541-2
LID - 10.1136/emj.2008.068767 [doi]
AB  - A case is presented in which a 66-year-old man received thrombolysis for an acute 
      ST elevation myocardial infarction (STEMI) within 6 minutes of developing chest 
      pain. An ECG performed 10 minutes after thrombolysis showed complete resolution 
      of the ST segment elevation and showed no other abnormality. An echocardiogram 
      showed normal left ventricular function and there was no detectable myocardial 
      necrosis, as evidenced by two negative troponin assays. The case clearly 
      reinforces the benefits of the rapid delivery of thrombolysis when appropriate 
      for patients with STEMI. Clinicians need to be aware of the benefits of early 
      thrombolysis as laid out in the national service framework. Evidence for the 
      early administration of thrombolysis, data from the Myocardial Infarction 
      National Audit Project and the future with regard to improving thrombolysis times 
      are discussed.
FAU - Suri, A
AU  - Suri A
AD  - Department of Cardiology, Royal Surrey County Hospital, Guildford, UK. 
      mrajaysuri@hotmail.com
FAU - Ahsan, S
AU  - Ahsan S
FAU - Lim, J
AU  - Lim J
FAU - Cusack, T-P
AU  - Cusack TP
FAU - Chua, T P
AU  - Chua TP
FAU - Leatham, E W
AU  - Leatham EW
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - England
TA  - Emerg Med J
JT  - Emergency medicine journal : EMJ
JID - 100963089
RN  - 0 (Fibrinolytic Agents)
RN  - EC 3.4.21.68 (Tissue Plasminogen Activator)
RN  - WGD229O42W (Tenecteplase)
SB  - IM
MH  - Aged
MH  - Electrocardiography
MH  - Fibrinolytic Agents/*therapeutic use
MH  - Humans
MH  - Male
MH  - Myocardial Infarction/*drug therapy
MH  - Myocardium/*pathology
MH  - Necrosis/prevention & control
MH  - Tenecteplase
MH  - Tissue Plasminogen Activator/*therapeutic use
EDAT- 2009/06/24 09:00
MHDA- 2009/11/18 06:00
CRDT- 2009/06/24 09:00
PHST- 2009/06/24 09:00 [entrez]
PHST- 2009/06/24 09:00 [pubmed]
PHST- 2009/11/18 06:00 [medline]
AID - 26/7/541 [pii]
AID - 10.1136/emj.2008.068767 [doi]
PST - ppublish
SO  - Emerg Med J. 2009 Jul;26(7):541-2. doi: 10.1136/emj.2008.068767.