PMID- 19548129
OWN - NLM
STAT- MEDLINE
DCOM- 20100924
LR  - 20101118
IS  - 1748-295X (Electronic)
IS  - 1748-2941 (Linking)
VI  - 11
IP  - 3
DP  - 2009
TI  - Acute hyperglycemia and spontaneous reperfusion in acute myocardial infarction.
PG  - 151-4
LID - 10.1080/17482940903039939 [doi]
AB  - BACKGROUND: Spontaneous reperfusion (SR) may occur in patients with ST elevation 
      myocardial infarction (STEMI) prior to reperfusion therapy. Hyperglycemia is 
      common on admission in patients with STEMI and is associated with a worse 
      prognosis. Mechanisms remain unclear but may include impairment of coronary flow. 
      The objective of this study was to examine whether acute hyperglycemia influenced 
      the occurrence of SR in patients with STEMI. METHODS: All patients presenting to 
      our institution with acute STEMI with measurement of glucose levels on 
      presentation were eligible. SR was defined as a combination of significant relief 
      of chest pain associated with an at least 70% resolution of ST segment elevation 
      on follow-up ECG. RESULTS: 465 patients were studied of whom 77 patients met 
      criteria for SR. Average glucose levels were not significantly different between 
      the SR and non-SR groups (10.0+/-5.6 mmol/l versus 10.1+/-5.3; P=NS). When 
      patients were divided into normoglycemic and hyperglycemic groups, there was no 
      significant difference in the percentages of such patients in the SR and non-SR 
      groups. (52% versus 54%; P=NS). CONCLUSIONS: Acute hyperglycemia on admission 
      does not predict the occurrence of SR in a general population of patients with 
      acute MI.
FAU - Leibowitz, David
AU  - Leibowitz D
AD  - Coronary Care Unit, Hadassah-Hebrew University Medical Center, Mount Scopus, 
      Jerusalem, Israel. oleibo@hadassah.org
FAU - Nowatzky, Johannes
AU  - Nowatzky J
FAU - Weiss, A Teddy
AU  - Weiss AT
FAU - Rott, David
AU  - Rott D
LA  - eng
PT  - Journal Article
PL  - England
TA  - Acute Card Care
JT  - Acute cardiac care
JID - 101276603
SB  - IM
MH  - Acute Disease
MH  - Adult
MH  - Aged
MH  - *Coronary Circulation
MH  - Electrocardiography
MH  - Female
MH  - Humans
MH  - Hyperglycemia/*complications/therapy
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/*complications/*physiopathology/therapy
MH  - Myocardial Reperfusion
MH  - Retrospective Studies
EDAT- 2009/06/24 09:00
MHDA- 2010/09/25 06:00
CRDT- 2009/06/24 09:00
PHST- 2009/06/24 09:00 [entrez]
PHST- 2009/06/24 09:00 [pubmed]
PHST- 2010/09/25 06:00 [medline]
AID - 912602932 [pii]
AID - 10.1080/17482940903039939 [doi]
PST - ppublish
SO  - Acute Card Care. 2009;11(3):151-4. doi: 10.1080/17482940903039939.