PMID- 19552028
OWN - NLM
STAT- MEDLINE
DCOM- 20090908
LR  - 20181201
IS  - 1682-8658 (Print)
IS  - 1682-8658 (Linking)
IP  - 2
DP  - 2009
TI  - [Gastroesophageal reflux disease: pathogenetic basis of differentiated tactics of 
      treatment].
PG  - 104-14
AB  - The article contains information about severe side effects of long-term acid 
      suppression with non-select proton pump inhibitors (PPI) treatment of 
      gastroesophageal reflux disease (GERD). As far as concern patients with heartborn 
      without esophagitis (non-erosive GERD) using PPI doesn't correspond the 
      pathogenesis and hardly has any advantages. Therapy with gastric acidity 
      inhibitors increases risk of acute gastroenteritis and community-acquired 
      pneumonia. Quality of life is rising and symptoms of gastro-esophageal reflux are 
      getting away thanks to topical harmless treatment GERD without severe esophagitis 
      Pepsan-R.
FAU - Tkachenko, E I
AU  - Tkachenko EI
FAU - Uspenskii, Iu P
AU  - Uspenskii IuP
FAU - Karateev, A E
AU  - Karateev AE
FAU - Bakulin, I G
AU  - Bakulin IG
FAU - Pakhomova, I G
AU  - Pakhomova IG
LA  - rus
PT  - Journal Article
PL  - Russia (Federation)
TA  - Eksp Klin Gastroenterol
JT  - Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical 
      gastroenterology
JID - 101144944
RN  - 0 (Gastrointestinal Agents)
RN  - 0 (Histamine H2 Antagonists)
RN  - 0 (Proton Pump Inhibitors)
SB  - IM
MH  - Dose-Response Relationship, Drug
MH  - Femoral Neck Fractures/epidemiology/etiology
MH  - Gastric Acid/metabolism
MH  - Gastroesophageal Reflux/*drug therapy/etiology/metabolism
MH  - Gastrointestinal Agents/administration & dosage/adverse effects/*therapeutic use
MH  - Histamine H2 Antagonists/administration & dosage/adverse effects/*therapeutic use
MH  - Humans
MH  - Pneumonia/epidemiology/etiology
MH  - Proton Pump Inhibitors/administration & dosage/*adverse effects/therapeutic use
MH  - Quality of Life
MH  - Time Factors
EDAT- 2009/06/26 09:00
MHDA- 2009/09/09 06:00
CRDT- 2009/06/26 09:00
PHST- 2009/06/26 09:00 [entrez]
PHST- 2009/06/26 09:00 [pubmed]
PHST- 2009/09/09 06:00 [medline]
PST - ppublish
SO  - Eksp Klin Gastroenterol. 2009;(2):104-14.