PMID- 19552677 OWN - NLM STAT- MEDLINE DCOM- 20100326 LR - 20100106 IS - 1365-2265 (Electronic) IS - 0300-0664 (Linking) VI - 72 IP - 1 DP - 2010 Jan TI - How should the patient with multiple endocrine neoplasia type 1 (MEN 1) be followed? PG - 13-6 LID - 10.1111/j.1365-2265.2009.03662.x [doi] AB - Multiple endocrine neoplasia type 1 (MEN 1) is a complex multi-system disease manifesting a diverse range of primary and secondary metabolic and neoplastic disorders. It is possible to improve patient prognosis by early disease detection and treatment. Regular biochemical and radiological screening for parathyroid, gastro-enteropancreatic, pituitary, intrathorasic and adrenal lesions forms the basis of surveillance. The likelihood of adverse sequelea such as renal and bone disease resulting from hyperparathyroidism, severe peptic ulceration and gastric carcinoidosis secondary to hypergastrinaemia can be ameliorated by early detection and management. FAU - Burgess, John AU - Burgess J AD - Department of Endocrinology, Royal Hobart Hospital, Hobart, TAS, Australia. jburges@postoffice.utas.edu.au LA - eng PT - Journal Article PT - Review DEP - 20090622 PL - England TA - Clin Endocrinol (Oxf) JT - Clinical endocrinology JID - 0346653 SB - IM MH - Cardiovascular Diseases/diagnosis/etiology/prevention & control MH - *Continuity of Patient Care MH - Follow-Up Studies MH - Humans MH - Hyperparathyroidism/diagnosis/etiology/prevention & control/therapy MH - Multiple Endocrine Neoplasia Type 1/complications/diagnosis/etiology/*therapy MH - Neoplasms/diagnosis/etiology/therapy MH - Risk Factors MH - Syndrome RF - 29 EDAT- 2009/06/26 09:00 MHDA- 2010/03/27 06:00 CRDT- 2009/06/26 09:00 PHST- 2009/06/26 09:00 [entrez] PHST- 2009/06/26 09:00 [pubmed] PHST- 2010/03/27 06:00 [medline] AID - CEN3662 [pii] AID - 10.1111/j.1365-2265.2009.03662.x [doi] PST - ppublish SO - Clin Endocrinol (Oxf). 2010 Jan;72(1):13-6. doi: 10.1111/j.1365-2265.2009.03662.x. Epub 2009 Jun 22.