PMID- 19555947
OWN - NLM
STAT- MEDLINE
DCOM- 20091201
LR  - 20121115
IS  - 1097-6779 (Electronic)
IS  - 0016-5107 (Linking)
VI  - 70
IP  - 3
DP  - 2009 Sep
TI  - Role of double-balloon endoscopy in the diagnosis of small-bowel tumors: the 
      first Japanese multicenter study.
PG  - 498-504
LID - 10.1016/j.gie.2008.12.242 [doi]
AB  - BACKGROUND: The early diagnosis of small-bowel tumors (SBT) was a difficult task 
      until the advent of capsule endoscopy (CE) and double-balloon endoscopy (DBE) 
      allowed access to the disease site. However, although CE and DBE have greatly 
      simplified the task, DBE studies have yet to provide sufficient data on the 
      diagnosis and outcome of patients with SBTs. OBJECTIVE: To determine the efficacy 
      of DBE examination in the detection and diagnosis of SBT. DESIGN: A retrospective 
      analysis of cross-sectional case series. SETTING: Seven major medical centers in 
      Japan. PATIENTS: The first 1035 consecutive DBE cases at these major Japanese 
      centers since the introduction of DBE. MAIN OUTCOME MEASUREMENTS: The percentage 
      of subjects with SBT and a diagnosis of SBT, their indications for DBE, and 
      diagnostic and therapeutic DBE procedures carried out for SBT. RESULTS: SBTs were 
      identified in 144 of 1035 subjects (13.9%) who underwent DBE between September 
      2000 and December 2005. For subjects with SBT, the most common indication for DBE 
      was the suspected presence of a SBT (61/144 [42.4%]). For subjects without SBT, 
      the most common indication was obscure GI bleeding (OGIB) (419/891 [47.0%]). 
      Malignant lymphoma and GI stromal tumor (GIST) were the most frequent (31/144 
      [21.5%]) and the second-most frequent SBTs (27/144 [18.8%]), respectively, in 
      this database. We also performed 85 biopsies and 45 therapeutic procedures for 
      the evaluation and treatment of SBTs in 144 patients. Although complications were 
      encountered in 5.3% of cases (14/266 sessions), none of these were life 
      threatening in the present study. CONCLUSION: DBE proved a valuable tool for the 
      detection and diagnosis of SBTs, especially when tumors were suspected. Biopsies 
      and therapeutic procedures were also possible in most of these patients, which 
      directed our management of the disease.
FAU - Mitsui, Keigo
AU  - Mitsui K
AD  - Division of Gastroenterology, Department of Medicine, Nippon Medical School, 
      Tokyo, Japan.
FAU - Tanaka, Shu
AU  - Tanaka S
FAU - Yamamoto, Hironori
AU  - Yamamoto H
FAU - Kobayashi, Tsuyoshi
AU  - Kobayashi T
FAU - Ehara, Akihito
AU  - Ehara A
FAU - Yano, Tomonori
AU  - Yano T
FAU - Goto, Hidemi
AU  - Goto H
FAU - Nakase, Hiroshi
AU  - Nakase H
FAU - Tanaka, Shinji
AU  - Tanaka S
FAU - Matsui, Toshiyuki
AU  - Matsui T
FAU - Iida, Mitsuo
AU  - Iida M
FAU - Sugano, Kentaro
AU  - Sugano K
FAU - Sakamoto, Choitsu
AU  - Sakamoto C
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Multicenter Study
DEP - 20090624
PL  - United States
TA  - Gastrointest Endosc
JT  - Gastrointestinal endoscopy
JID - 0010505
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Age Distribution
MH  - Aged
MH  - Aged, 80 and over
MH  - Capsule Endoscopes
MH  - Capsule Endoscopy/methods
MH  - Catheterization/*instrumentation
MH  - Cross-Sectional Studies
MH  - Early Detection of Cancer
MH  - *Endoscopes, Gastrointestinal
MH  - Endoscopy, Gastrointestinal/*methods
MH  - Female
MH  - Humans
MH  - Incidence
MH  - Intestinal Neoplasms/*diagnosis/epidemiology
MH  - Intestine, Small/*pathology
MH  - Japan
MH  - Male
MH  - Middle Aged
MH  - Retrospective Studies
MH  - Risk Assessment
MH  - Sensitivity and Specificity
MH  - Sex Distribution
MH  - Young Adult
EDAT- 2009/06/27 09:00
MHDA- 2009/12/16 06:00
CRDT- 2009/06/27 09:00
PHST- 2008/08/31 00:00 [received]
PHST- 2008/12/23 00:00 [accepted]
PHST- 2009/06/27 09:00 [entrez]
PHST- 2009/06/27 09:00 [pubmed]
PHST- 2009/12/16 06:00 [medline]
AID - S0016-5107(08)03418-4 [pii]
AID - 10.1016/j.gie.2008.12.242 [doi]
PST - ppublish
SO  - Gastrointest Endosc. 2009 Sep;70(3):498-504. doi: 10.1016/j.gie.2008.12.242. Epub 
      2009 Jun 24.