PMID- 1955829
OWN - NLM
STAT- MEDLINE
DCOM- 19920102
LR  - 20131121
IS  - 0022-1198 (Print)
IS  - 0022-1198 (Linking)
VI  - 36
IP  - 5
DP  - 1991 Sep
TI  - Simultaneous analysis of amphetamine, methamphetamine, and 3, 
      4-methylenedioxymethamphetamine (MDMA) in urine samples by solid-phase 
      extraction, derivatization, and gas chromatography/mass spectrometry.
PG  - 1331-41
AB  - A rapid and effective solid-phase extraction procedure using Bond Elute Certify 
      bonded silica sorbent cartridges was adopted to extract amphetamine, 
      methamphetamine, and 3,4-methylenedioxymethamphetamine (MDMA or Ecstasy) from 
      urine samples. The extract was derivatized with trichloroacetic anhydride prior 
      to gas chromatography/mass spectrometry (GC/MS) analysis with selected ion 
      monitoring of the following ions: 190, 91, 188; 204, 91, 202; 162, 135, 202; 194, 
      123; and 211, 209 for the derivatized amphetamine, methamphetamine, MDMA, 
      d5-amphetamine, and d9-methamphetamine, respectively. The first of the ions 
      listed for each compound was used for quantitation. The compound d5-amphetamine 
      was used as the internal standard for amphetamine, and d9-methamphetamine was 
      used for methamphetamine and MDMA. Results showed a higher than 65% recovery and 
      a reproducibility with less than a 5% coefficient of variation. When a sample 
      size of 2 mL was used, the lowest detectable concentration was about 50 ng/mL, 
      and a near-perfect fit can be obtained (within the 250 to 4000-ng/mL 
      concentration range studied) using a second-order polynomial model.
FAU - Gan, B K
AU  - Gan BK
AD  - Department of Criminal Justice, University of Alabama, Birmingham.
FAU - Baugh, D
AU  - Baugh D
FAU - Liu, R H
AU  - Liu RH
FAU - Walia, A S
AU  - Walia AS
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Forensic Sci
JT  - Journal of forensic sciences
JID - 0375370
RN  - 44RAL3456C (Methamphetamine)
RN  - 4764-17-4 (3,4-Methylenedioxyamphetamine)
RN  - CK833KGX7E (Amphetamine)
SB  - IM
MH  - 3,4-Methylenedioxyamphetamine/*urine
MH  - Amphetamine/*urine
MH  - Calibration
MH  - Gas Chromatography-Mass Spectrometry
MH  - Humans
MH  - Methamphetamine/*urine
MH  - Predictive Value of Tests
MH  - Reproducibility of Results
EDAT- 1991/09/01 00:00
MHDA- 1991/09/01 00:01
CRDT- 1991/09/01 00:00
PHST- 1991/09/01 00:00 [pubmed]
PHST- 1991/09/01 00:01 [medline]
PHST- 1991/09/01 00:00 [entrez]
PST - ppublish
SO  - J Forensic Sci. 1991 Sep;36(5):1331-41.