PMID- 19576591
OWN - NLM
STAT- MEDLINE
DCOM- 20090903
LR  - 20090717
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1216
IP  - 32
DP  - 2009 Aug 7
TI  - Multiresidue determination of 11 new fungicides in grapes and wines by 
      liquid-liquid extraction/clean-up and programmable temperature vaporization 
      injection with analyte protectants/gas chromatography/ion trap mass spectrometry.
PG  - 6033-42
LID - 10.1016/j.chroma.2009.06.046 [doi]
AB  - A gas chromatographic ion trap mass spectrometry (GC-ITMS) method was developed 
      for the determination of 11 new generation fungicides (benalaxyl, benalaxyl-M, 
      boscalid, cyazofamid, famoxadone, fenamidone, fluquinconazole, iprovalicarb, 
      pyraclostrobin, trifloxystrobin and zoxamide) in grapes and wines. Samples were 
      extracted with ethyl acetate:hexane (1:1, v/v) and cleaned-up with graphitized 
      carbon black/primary secondary amine (GCB/PSA) solid-phase extraction (SPE) 
      cartridges using acetonitrile:toluene (3:1, v/v) as eluent. The addition of 
      analyte protectants (3-ethoxy-1,2-propanediol, d-sorbitol and l-gulonic acid 
      gamma-lactone) in the final extracts allowed to avoid the matrix-induced response 
      enhancement effect on quantitation process with absolute recoveries ca. 100%. 
      Precision (expressed as relative standard deviation) was lower than 16% for all 
      fungicides. Limits of detection and quantitation were lower than 0.01 mg/kg or 
      mg/L, except for cyazofamid, much smaller in all cases than maximum residue 
      levels (MRLs) established by European Union for grapes and by Switzerland and 
      Italy for wines. The proposed method was applied to determine fungicide residues 
      in three different white grapes for vinification produced in Ribeiro area in 
      Galicia (NW Spain), as well as in their corresponding final wines.
FAU - Gonzalez-Rodriguez, Rosa M
AU  - Gonzalez-Rodriguez RM
AD  - Nutrition and Bromatology Group, Analytical and Food Chemistry Department, 
      Faculty of Food Science and Technology, University of Vigo, Ourense Campus, 
      E32400 Ourense, Spain.
FAU - Cancho-Grande, Beatriz
AU  - Cancho-Grande B
FAU - Simal-Gandara, Jesus
AU  - Simal-Gandara J
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20090618
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Fungicides, Industrial)
RN  - 0 (Pesticide Residues)
SB  - IM
MH  - Chemical Fractionation/methods
MH  - Fungicides, Industrial/*analysis
MH  - Gas Chromatography-Mass Spectrometry/*methods
MH  - Linear Models
MH  - Pesticide Residues/*analysis
MH  - Reproducibility of Results
MH  - Sensitivity and Specificity
MH  - Temperature
MH  - Vitis/*chemistry
MH  - Volatilization
MH  - Wine/*analysis
EDAT- 2009/07/07 09:00
MHDA- 2009/09/04 06:00
CRDT- 2009/07/07 09:00
PHST- 2009/02/10 00:00 [received]
PHST- 2009/06/09 00:00 [revised]
PHST- 2009/06/12 00:00 [accepted]
PHST- 2009/07/07 09:00 [entrez]
PHST- 2009/07/07 09:00 [pubmed]
PHST- 2009/09/04 06:00 [medline]
AID - S0021-9673(09)00914-5 [pii]
AID - 10.1016/j.chroma.2009.06.046 [doi]
PST - ppublish
SO  - J Chromatogr A. 2009 Aug 7;1216(32):6033-42. doi: 10.1016/j.chroma.2009.06.046. 
      Epub 2009 Jun 18.