PMID- 1957756
OWN - NLM
STAT- MEDLINE
DCOM- 19911231
LR  - 20190626
IS  - 0002-8703 (Print)
IS  - 0002-8703 (Linking)
VI  - 122
IP  - 6
DP  - 1991 Dec
TI  - Diagnostic accuracy of peak exercise echocardiography in coronary artery disease: 
      comparison with thallium-201 myocardial scintigraphy.
PG  - 1609-16
AB  - To evaluate the accuracy of exercise two-dimensional echocardiography for the 
      recognition of coronary artery disease, 53 patients (46 men and 7 women, age 
      range 35 to 69 years) without either previous myocardial infarction or resting 
      wall motion abnormalities, were studied. According to coronary angiography 26 had 
      normal coronary arteries, 14 had one-vessel, seven had two-vessel, and six had 
      three-vessel disease. After withdrawal of any therapy, all patients underwent a 
      single exercise stress test with a stress table during which cine-loop digitized 
      echocardiography was acquired and 74 MBq of thallium-201 (TI-201) were injected. 
      Echocardiographic images were evaluated at rest and at peak exercise. Three-view 
      planar scintigraphic images were collected immediately after exercise and 4 hours 
      later. For the overall recognition of coronary artery disease, exercise 
      electrocardiography had 77.8% sensitivity and 65.4% specificity; myocardial 
      scintigraphy had 100% sensitivity and 92.3% specificity; and exercise 
      echocardiography had 92.6% sensitivity and 96.2% specificity (both NS versus 
      myocardial scintigraphy). Global accuracy was 71.7% for exercise 
      electrocardiography, 94.3% for stress echocardiography, and 96.2% for myocardial 
      scintigraphy. For the classification of the individual involved coronary 
      arteries, the sensitivity of myocardial scintigraphy was 84.8% and that of 
      exercise echocardiography was 63% (p less than 0.01); the related specificities 
      were 98% and 98.2% respectively (NS). It may be concluded that exercise 
      echocardiography is highly accurate for the recognition of coronary artery 
      disease, whereas it appears less sensitive in the identification of the involved 
      vessels, particularly in patients with multivessel disease.
FAU - Galanti, G
AU  - Galanti G
AD  - Istituto di Clinica Medica 1, Firenze, Italy.
FAU - Sciagra, R
AU  - Sciagra R
FAU - Comeglio, M
AU  - Comeglio M
FAU - Taddei, T
AU  - Taddei T
FAU - Bonechi, F
AU  - Bonechi F
FAU - Giusti, F
AU  - Giusti F
FAU - Malfanti, P
AU  - Malfanti P
FAU - Bisi, G
AU  - Bisi G
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - Am Heart J
JT  - American heart journal
JID - 0370465
RN  - 0 (Thallium Radioisotopes)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Cardiac Catheterization
MH  - Coronary Angiography
MH  - Coronary Disease/*diagnosis
MH  - Echocardiography/*methods
MH  - Evaluation Studies as Topic
MH  - Exercise Test/methods
MH  - Female
MH  - Heart/*diagnostic imaging
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Radionuclide Imaging
MH  - Sensitivity and Specificity
MH  - *Thallium Radioisotopes
EDAT- 1991/12/01 00:00
MHDA- 1991/12/01 00:01
CRDT- 1991/12/01 00:00
PHST- 1991/12/01 00:00 [pubmed]
PHST- 1991/12/01 00:01 [medline]
PHST- 1991/12/01 00:00 [entrez]
AID - 0002-8703(91)90278-P [pii]
AID - 10.1016/0002-8703(91)90278-p [doi]
PST - ppublish
SO  - Am Heart J. 1991 Dec;122(6):1609-16. doi: 10.1016/0002-8703(91)90278-p.