PMID- 19581917
OWN - NLM
STAT- MEDLINE
DCOM- 20100513
LR  - 20110606
IS  - 1476-5624 (Electronic)
IS  - 1362-4393 (Linking)
VI  - 48
IP  - 2
DP  - 2010 Feb
TI  - Low-back pain in HTLV-I-associated myelopathy/tropical spastic paraparesis: 
      nociceptive or neuropathic?
PG  - 134-7
LID - 10.1038/sc.2009.83 [doi]
AB  - STUDY DESIGN: Cross-sectional. OBJECTIVES: To describe characteristics of 
      low-back pain in human T-cell lymphotropic virus type I (HTLV-I)-associated 
      myelopathy/tropical spastic paraparesis (HAM/TSP) patients and to identify its 
      neuropathic and/or non-neuropathic pain components. SETTING: A reference center 
      for the care of patients with HAM/TSP in Rio de Janeiro, Brazil. METHODS: A total 
      of 90 patients with HAM/TSP referred by tertiary care centers were consecutively 
      assessed. The patients were submitted to a clinical protocol that included Visual 
      Analogue Scale (VAS), Timed Up and Go Test, Bodily Pain Domain of the Short Form 
      36 Health Status Questionnaire, Douleur Neuropathique 4 Questions (Neuropathic 
      Pain 4 Questions) (DN4) and McGill Pain Questionnaire. RESULTS: The prevalence of 
      low-back pain in the studied sample was 75.5%; pain interferes with physical 
      functioning and worsens with movement and physical effort. It can be relieved by 
      analgesics and rest. Average pain intensity was 51.2 mm on VAS and 1.72 on DN4. 
      The most frequent words used to describe low-back pain were throbbing, burning, 
      jumping and aching. Surprisingly, 32.4% patients pointed the lower extremities as 
      the most painful and used different descriptors. The most common drugs used were 
      analgesics, nonsteroidal anti-inflammatory drugs and tricyclic antidepressants. 
      CONCLUSIONS: Low-back pain in HAM/TSP patients has mainly nociceptive 
      characteristics. Conversely, descriptors for lower extremities pain suggest a 
      neuropathic origin.
FAU - Tavares, I R
AU  - Tavares IR
AD  - Clementino Fraga Filho University Hospital, The Federal University of Rio de 
      Janeiro, Rio de Janeiro, Brazil. rangelir@yahoo.com.br
FAU - Franzoi, A C
AU  - Franzoi AC
FAU - Araujo, A Q-C
AU  - Araujo AQ
LA  - eng
PT  - Journal Article
DEP - 20090707
PL  - England
TA  - Spinal Cord
JT  - Spinal cord
JID - 9609749
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Brazil
MH  - Child
MH  - Child, Preschool
MH  - Cross-Sectional Studies
MH  - Female
MH  - Health Surveys
MH  - Humans
MH  - Infant
MH  - Infant, Newborn
MH  - Low Back Pain/epidemiology/*physiopathology
MH  - Lower Extremity/physiopathology
MH  - Male
MH  - Middle Aged
MH  - Nociceptors/*physiology
MH  - Pain Measurement
MH  - Paraparesis, Tropical Spastic/*complications/*physiopathology
MH  - Prevalence
MH  - Young Adult
EDAT- 2009/07/08 09:00
MHDA- 2010/05/14 06:00
CRDT- 2009/07/08 09:00
PHST- 2009/07/08 09:00 [entrez]
PHST- 2009/07/08 09:00 [pubmed]
PHST- 2010/05/14 06:00 [medline]
AID - sc200983 [pii]
AID - 10.1038/sc.2009.83 [doi]
PST - ppublish
SO  - Spinal Cord. 2010 Feb;48(2):134-7. doi: 10.1038/sc.2009.83. Epub 2009 Jul 7.