PMID- 19583149
OWN - NLM
STAT- MEDLINE
DCOM- 20090818
LR  - 20190917
IS  - 0042-8450 (Print)
IS  - 0042-8450 (Linking)
VI  - 66
IP  - 6
DP  - 2009 Jun
TI  - [Unilatelaral iris plateau syndrome after the use of ecstasy].
PG  - 487-9
AB  - BACKGROUND: Courmon street name for 3,4-Methylenedioxymethamphetamine (MDMA) is 
      ecstasy. This widely abused "recreational" drug causes both an increased release 
      of monoamine neurotransmitters, including serotonine and dopamine, and an 
      increased reuptake inhibition of serotonin. As a consequence, mydriasis and 
      increased intraocular pressure (IOP) in predisposed patients occur. We present 
      herein a rare case of acute increased IOP after use of ecstasy. CASE REPORT: A 
      female patient, aged 38 years, visited doctor complaing of a decreased vision 
      acuity and severe pain in the left eye and in the left part of the head. The 
      initial treatment was urgent antiglaucomatous therapy followed by withdrawal of 
      subjective problems of the patient and improvement of objective finding. History 
      taking procedure revaled that just before the onset of the pain the patient had 
      used ecstasy and had had similar "experience" 6 years ago after cocaine snorting. 
      She had not been to a doctor although she had experienced sporadic migrenous 
      pain. Previous medical records excavation of revealed optic disk (cup-to-dise 
      C/D=06), Bjerum arcuate scotoma and iris plateau with narrow chamber angle 
      (Scheie II-III) so the diagnosis was a rare unilateral iris plateau syndrome of 
      the left eye. Although the patient was given some pieces of information about the 
      dangerous and possible deadly consequences of psychoactive substanace abuse, she 
      has not continue the treatment. CONCLUSION: Ecstasy abuse might cause a complete 
      loss of vision, thus medicametous and surgical treatment are abligatory.
FAU - Jovanovic, Predrag
AU  - Jovanovic P
AD  - Klinicki centar, Klinika za ocne bolesti, Nis, Srbija. pedjaj@bankerinter.net
FAU - Hentova-Sencanic, Paraskeva
AU  - Hentova-Sencanic P
FAU - Zoric, Lepsa
AU  - Zoric L
FAU - Petrovic, Maja
AU  - Petrovic M
FAU - Bozinovic, Marija Trenkic
AU  - Bozinovic MT
LA  - srp
PT  - Case Reports
PT  - English Abstract
PT  - Journal Article
PL  - Serbia
TA  - Vojnosanit Pregl
JT  - Vojnosanitetski pregled
JID - 21530700R
RN  - 0 (Hallucinogens)
RN  - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine)
SB  - IM
MH  - Adult
MH  - Female
MH  - Hallucinogens/*adverse effects
MH  - Humans
MH  - Intraocular Pressure/drug effects
MH  - N-Methyl-3,4-methylenedioxyamphetamine/*adverse effects
MH  - Ocular Hypertension/chemically induced
MH  - Substance-Related Disorders/*complications
EDAT- 2009/07/09 09:00
MHDA- 2009/08/19 09:00
CRDT- 2009/07/09 09:00
PHST- 2009/07/09 09:00 [entrez]
PHST- 2009/07/09 09:00 [pubmed]
PHST- 2009/08/19 09:00 [medline]
AID - 10.2298/vsp0906487j [doi]
PST - ppublish
SO  - Vojnosanit Pregl. 2009 Jun;66(6):487-9. doi: 10.2298/vsp0906487j.