PMID- 19583455
OWN - NLM
STAT- MEDLINE
DCOM- 20091030
LR  - 20211020
IS  - 1179-1950 (Electronic)
IS  - 0012-6667 (Linking)
VI  - 69
IP  - 10
DP  - 2009 Jul 9
TI  - Rabeprazole: a review of its use in the management of gastric acid-related 
      diseases in adults.
PG  - 1373-401
LID - 10.2165/00003495-200969100-00007 [doi]
AB  - Rabeprazole (Aciphex, Alfence, Pariet) is a proton pump inhibitor (PPI) used for 
      the treatment of adults with conditions requiring a reduction of gastric acid 
      secretion such as erosive or ulcerative gastro-oesophageal reflux disease (GORD), 
      non-erosive reflux disease (NERD), duodenal and gastric ulcers, and pathological 
      hypersecretory conditions including Zollinger-Ellison syndrome (ZES). It is also 
      used as part of combination therapy for the eradication of Helicobacter pylori, a 
      pathogen frequently implicated in the development of gastric and duodenal ulcers. 
      Rabeprazole has a well established efficacy and safety profile in the treatment 
      of gastric acid-related diseases. Rabeprazole is a useful, well tolerated and 
      cost-effective option for the treatment of GORD, NERD, peptic ulcer and other 
      gastric acid-related diseases (including ZES), and provides an appropriate 
      alternative to other currently available PPIs, with the added benefits of having 
      a consistent efficacy profile and low drug interaction potential due to its 
      predominantly nonenzymatic metabolism.
FAU - Baldwin, Claudine M
AU  - Baldwin CM
AD  - Wolters Kluwer Health, Adis, Auckland, New Zealand. demail@adis.co.nz
FAU - Keam, Susan J
AU  - Keam SJ
LA  - eng
PT  - Journal Article
PT  - Review
PL  - New Zealand
TA  - Drugs
JT  - Drugs
JID - 7600076
RN  - 0 (2-Pyridinylmethylsulfinylbenzimidazoles)
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Proton Pump Inhibitors)
RN  - 32828355LL (Rabeprazole)
SB  - IM
MH  - 2-Pyridinylmethylsulfinylbenzimidazoles/administration & 
      dosage/economics/pharmacokinetics/pharmacology/*therapeutic use
MH  - Adult
MH  - Anti-Bacterial Agents/pharmacology
MH  - Gastric Acid/metabolism/*physiology
MH  - Gastroesophageal Reflux/drug therapy
MH  - Gastrointestinal Diseases/*drug therapy/economics
MH  - Helicobacter Infections/drug therapy
MH  - Humans
MH  - Peptic Ulcer/drug therapy/microbiology
MH  - Proton Pump Inhibitors/administration & 
      dosage/economics/pharmacokinetics/pharmacology/*therapeutic use
MH  - Quality of Life
MH  - Rabeprazole
RF  - 92
EDAT- 2009/07/09 09:00
MHDA- 2009/10/31 06:00
CRDT- 2009/07/09 09:00
PHST- 2009/07/09 09:00 [entrez]
PHST- 2009/07/09 09:00 [pubmed]
PHST- 2009/10/31 06:00 [medline]
AID - 7 [pii]
AID - 10.2165/00003495-200969100-00007 [doi]
PST - ppublish
SO  - Drugs. 2009 Jul 9;69(10):1373-401. doi: 10.2165/00003495-200969100-00007.