PMID- 19588282 OWN - NLM STAT- MEDLINE DCOM- 20091124 LR - 20131121 IS - 1747-0927 (Electronic) IS - 1747-0919 (Linking) VI - 4 IP - 5 DP - 2009 TI - Is the self special in the dorsomedial prefrontal cortex? An fMRI study. PG - 455-63 LID - 10.1080/17470910903027808 [doi] AB - In recent years, several neuroimaging studies have suggested that the neural basis of the self-referential process1 is special, especially in the medial prefrontal cortex (MPFC). However, it remains controversial whether activity of the MPFC (and other related brain regions) appears only during the self-referential process. We investigated the neural correlates during the processing of references to the self, close other (friend), and distant other (prime minister) using fMRI. In comparison with baseline findings, referential processing to the three kinds of persons defined above showed common activation patterns in the dorsomedial prefrontal cortex (DMPFC), left middle temporal gyrus, left angular gyrus, posterior cingulate cortex and right cerebellum. Additionally, percent changes in BOLD signal in five regions of interest demonstrated the same findings. The result indicated that DMPFC was not special for the self-referential process, while there are common neural bases for evaluating the personalities of the self and others. FAU - Yaoi, Ken AU - Yaoi K AD - Kyoto University, Kyoto, Japan. fin3@t02.mbox.media.kyoto-u.ac.jp FAU - Osaka, Naoyuki AU - Osaka N FAU - Osaka, Mariko AU - Osaka M LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20090708 PL - England TA - Soc Neurosci JT - Social neuroscience JID - 101279009 RN - S88TT14065 (Oxygen) SB - IM MH - Adult MH - *Brain Mapping MH - Female MH - Humans MH - Image Processing, Computer-Assisted/methods MH - *Magnetic Resonance Imaging MH - Male MH - Oxygen/blood MH - *Personality MH - Photic Stimulation/methods MH - Prefrontal Cortex/blood supply/*physiology MH - Reaction Time/physiology MH - *Self Concept MH - Social Desirability MH - Time Factors MH - Young Adult EDAT- 2009/07/10 09:00 MHDA- 2009/12/16 06:00 CRDT- 2009/07/10 09:00 PHST- 2009/07/10 09:00 [entrez] PHST- 2009/07/10 09:00 [pubmed] PHST- 2009/12/16 06:00 [medline] AID - 912991736 [pii] AID - 10.1080/17470910903027808 [doi] PST - ppublish SO - Soc Neurosci. 2009;4(5):455-63. doi: 10.1080/17470910903027808. Epub 2009 Jul 8.