PMID- 19590139
OWN - NLM
STAT- MEDLINE
DCOM- 20091105
LR  - 20190819
IS  - 1347-4820 (Electronic)
IS  - 1346-9843 (Linking)
VI  - 73
IP  - 9
DP  - 2009 Sep
TI  - Clinical impact of atrial fibrillation in patients with hypertrophic 
      cardiomyopathy. Results from Kochi RYOMA Study.
PG  - 1599-605
AB  - BACKGROUND: There have been few studies of the clinical features of hypertrophic 
      cardiomyopathy (HCM) in a community-based patient cohort in Japan. METHODS AND 
      RESULTS: Cardiomyopathy registration was established in Kochi Prefecture and 
      named the Kochi RYOMA (registry of myocardial diseases) study, consisting of 9 
      hospitals that registered 261 patients with a diagnosis of HCM. At registration, 
      74 patients (28%) had documented paroxysmal or chronic atrial fibrillation (AF). 
      Although most patients (93%) were in New York Heart Association (NYHA) class I or 
      II, 17 of the 18 patients in NYHA III had AF; 37 of the 74 patients with AF 
      suffered from morbid events (embolism and/or heart failure (HF) admission), and 
      15 of 19 patients with embolic events had AF prior to or at the time of embolism. 
      Of the 29 patients who had a history of HF admission, 8 had left ventricular 
      systolic dysfunction, and the other 21 patients were hospitalized because of 
      diastolic HF. AF occurred prior to HF in 20 of those 21 patients. Furthermore, 19 
      of those 20 patients with AF and diastolic HF were hospitalized within 1 year 
      after detection of AF. CONCLUSIONS: In an unselected regional registry, AF was 
      the major determinant of clinical deteriorations in patients with HCM.
FAU - Kubo, Toru
AU  - Kubo T
AD  - Department of Medicine and Geriatrics, Kochi Medical School, Nankoku, Japan.
FAU - Kitaoka, Hiroaki
AU  - Kitaoka H
FAU - Okawa, Makoto
AU  - Okawa M
FAU - Hirota, Takayoshi
AU  - Hirota T
FAU - Hayato, Kayo
AU  - Hayato K
FAU - Yamasaki, Naohito
AU  - Yamasaki N
FAU - Matsumura, Yoshihisa
AU  - Matsumura Y
FAU - Yabe, Toshikazu
AU  - Yabe T
FAU - Takata, Jun
AU  - Takata J
FAU - Doi, Yoshinori L
AU  - Doi YL
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
DEP - 20090709
PL  - Japan
TA  - Circ J
JT  - Circulation journal : official journal of the Japanese Circulation Society
JID - 101137683
SB  - IM
CIN - Circ J. 2009 Sep;73(9):1589-90. PMID: 19706983
MH  - Adolescent
MH  - Adult
MH  - Age Distribution
MH  - Aged
MH  - Aged, 80 and over
MH  - Atrial Fibrillation/*epidemiology/etiology/therapy
MH  - Cardiomyopathy, Hypertrophic/complications/*epidemiology/therapy
MH  - Child
MH  - Disease Progression
MH  - Embolism/*epidemiology/etiology/therapy
MH  - Female
MH  - Heart Failure/*epidemiology/etiology/therapy
MH  - Humans
MH  - Japan/epidemiology
MH  - Male
MH  - Middle Aged
MH  - Prevalence
MH  - Registries
MH  - Retrospective Studies
MH  - Severity of Illness Index
MH  - Time Factors
MH  - Young Adult
EDAT- 2009/07/11 09:00
MHDA- 2009/11/06 06:00
CRDT- 2009/07/11 09:00
PHST- 2009/07/11 09:00 [entrez]
PHST- 2009/07/11 09:00 [pubmed]
PHST- 2009/11/06 06:00 [medline]
AID - JST.JSTAGE/circj/CJ-09-0140 [pii]
AID - 10.1253/circj.cj-09-0140 [doi]
PST - ppublish
SO  - Circ J. 2009 Sep;73(9):1599-605. doi: 10.1253/circj.cj-09-0140. Epub 2009 Jul 9.